TY - JOUR
T1 - Executive function improvement in normal pressure hydrocephalus following shunt surgery
AU - Gleichgerrcht, Ezequiel
AU - Cervio, Andrés
AU - Salvat, Jorge
AU - Loffredo, A. R.
AU - Vita, Luciana
AU - Roca, María
AU - Torralva, Teresa
AU - Manes, Facundo
PY - 2009
Y1 - 2009
N2 - The aim of this investigation was to evaluate improvement of executive functions after shunt surgery in patients with early normal pressure hydrocephalus (NPH). Patients with NPH were assessed before and after shunt surgery with tests shown to be sensitive to damage to the prefrontal cortex (PFC). Significant differences were found between basal and follow-up performances on the Boston Naming Test, the backwards digits span, Part B of the Trail Making Test, and the number of words produced on the phonological fluency task. In conclusion, our study reveals that patients with NPH who respond positively to continuous slow lumbar cerebral spinal fluid drainage and receive a ventriculoperitoneal shunt implant, improve their performance on tasks of executive function. Due to the high demand for this form of mental processing in real-life complex scenarios, and based on the severe executive deficits present in both demented and non-demented NPH patients, we encourage the assessment of executive functions in this clinical group.
AB - The aim of this investigation was to evaluate improvement of executive functions after shunt surgery in patients with early normal pressure hydrocephalus (NPH). Patients with NPH were assessed before and after shunt surgery with tests shown to be sensitive to damage to the prefrontal cortex (PFC). Significant differences were found between basal and follow-up performances on the Boston Naming Test, the backwards digits span, Part B of the Trail Making Test, and the number of words produced on the phonological fluency task. In conclusion, our study reveals that patients with NPH who respond positively to continuous slow lumbar cerebral spinal fluid drainage and receive a ventriculoperitoneal shunt implant, improve their performance on tasks of executive function. Due to the high demand for this form of mental processing in real-life complex scenarios, and based on the severe executive deficits present in both demented and non-demented NPH patients, we encourage the assessment of executive functions in this clinical group.
KW - Cognitive recovery
KW - Executive functions
KW - Neuropsychological testing
KW - Normal pressure hydrocephalus
KW - Ventriculoperitoneal shunt
UR - http://www.scopus.com/inward/record.url?scp=72949123422&partnerID=8YFLogxK
U2 - 10.3233/BEN-2009-0249
DO - 10.3233/BEN-2009-0249
M3 - Article
C2 - 19996515
AN - SCOPUS:72949123422
SN - 0953-4180
VL - 21
SP - 181
EP - 185
JO - Behavioural Neurology
JF - Behavioural Neurology
IS - 3-4
ER -