Executive function improvement in normal pressure hydrocephalus following shunt surgery

Ezequiel Gleichgerrcht, Andrés Cervio, Jorge Salvat, A. R. Loffredo, Luciana Vita, María Roca, Teresa Torralva, Facundo Manes*

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    18 Citations (Scopus)


    The aim of this investigation was to evaluate improvement of executive functions after shunt surgery in patients with early normal pressure hydrocephalus (NPH). Patients with NPH were assessed before and after shunt surgery with tests shown to be sensitive to damage to the prefrontal cortex (PFC). Significant differences were found between basal and follow-up performances on the Boston Naming Test, the backwards digits span, Part B of the Trail Making Test, and the number of words produced on the phonological fluency task. In conclusion, our study reveals that patients with NPH who respond positively to continuous slow lumbar cerebral spinal fluid drainage and receive a ventriculoperitoneal shunt implant, improve their performance on tasks of executive function. Due to the high demand for this form of mental processing in real-life complex scenarios, and based on the severe executive deficits present in both demented and non-demented NPH patients, we encourage the assessment of executive functions in this clinical group.

    Original languageEnglish
    Pages (from-to)181-185
    Number of pages5
    JournalBehavioural Neurology
    Issue number3-4
    Publication statusPublished - 2009


    • Cognitive recovery
    • Executive functions
    • Neuropsychological testing
    • Normal pressure hydrocephalus
    • Ventriculoperitoneal shunt


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