TY - JOUR
T1 - Executive functioning in obsessive-compulsive disorder, unipolar depression, and schizophrenia
AU - Moritz, Steffen
AU - Birkner, Christiane
AU - Kloss, Martin
AU - Jahn, Holger
AU - Hand, Iver
AU - Haasen, Christian
AU - Krausz, Michael
PY - 2002
Y1 - 2002
N2 - The present study investigated whether schizophrenic, unipolar depressive, and obsessive-compulsive psychiatric patients show a distinguishable profile in tasks considered sensitive to frontal lobe functioning. Three psychiatric samples, each comprising 25 patients with little symptomatic overlap, were compared to 70 healthy controls. Participants completed several executive tasks (Wisconsin Card Sorting Test (WCST), verbal fluency, digit span, Stroop, and Trail-Making). Except for age, which was entered as a covariate, subjects did not differ in any sociodemographic background variable. Healthy controls showed superior performance relative to depressive and schizophrenic patients who exhibited comparable deficits in all tasks. Obsessive-compulsive disorder (OCD) patients revealed dysfunctions in the Trail-Making Tests A and B and in the fluency task. Dysfunctions in the domains of working memory, verbal fluency, distractibility, and concept formation were not confined to a specific psychiatric population.
AB - The present study investigated whether schizophrenic, unipolar depressive, and obsessive-compulsive psychiatric patients show a distinguishable profile in tasks considered sensitive to frontal lobe functioning. Three psychiatric samples, each comprising 25 patients with little symptomatic overlap, were compared to 70 healthy controls. Participants completed several executive tasks (Wisconsin Card Sorting Test (WCST), verbal fluency, digit span, Stroop, and Trail-Making). Except for age, which was entered as a covariate, subjects did not differ in any sociodemographic background variable. Healthy controls showed superior performance relative to depressive and schizophrenic patients who exhibited comparable deficits in all tasks. Obsessive-compulsive disorder (OCD) patients revealed dysfunctions in the Trail-Making Tests A and B and in the fluency task. Dysfunctions in the domains of working memory, verbal fluency, distractibility, and concept formation were not confined to a specific psychiatric population.
KW - Depression
KW - Frontal lobe
KW - Obsessive-compulsive disorder
KW - Schizophrenia
KW - Verbal fluency
KW - Wisconsin Card Sorting Test
UR - http://www.scopus.com/inward/record.url?scp=0036280328&partnerID=8YFLogxK
U2 - 10.1016/S0887-6177(01)00130-5
DO - 10.1016/S0887-6177(01)00130-5
M3 - Article
C2 - 14592001
AN - SCOPUS:0036280328
VL - 17
SP - 477
EP - 483
JO - Archives of Clinical Neuropsychology
JF - Archives of Clinical Neuropsychology
SN - 0887-6177
IS - 5
ER -