Exogenous iron redistribution between brain and liver after administering 57Fe3O4 ferrofluid to a rat brain ventricle

R. R. Gabbasov*, V. M. Cherepanov, M. A. Chuev, I. N. Mishchenko, D. M. Polikarpov, N. A. Loginova, E. V. Loseva, M. P. Nikitin, V. Y. Panchenko

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The natural excretion of 57Fe enriched magnetic nanoparticles from a rat’s brain through its blood–brain barrier is studied. Dextran-coated iron oxide nanoparticles are transcranially injected into the rat’s brain ventricle. The injected nanoparticles undergo biotransformation into iron-containing proteins distributed over the brain tissues, while the exogenous iron transported from the brain to other organs is eliminated from the body over time.

Original languageEnglish
Pages (from-to)788-792
Number of pages5
JournalBulletin of the Russian Academy of Sciences: Physics
Volume81
Issue number7
DOIs
Publication statusPublished - 1 Jul 2017

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