Exogenous iron redistribution between brain and liver after administering 57Fe3O4 ferrofluid to a rat brain ventricle

R. R. Gabbasov; V. M. Cherepanov; M. A. Chuev; I. N. Mishchenko; D. M. Polikarpov; N. A. Loginova; E. V. Loseva; M. P. Nikitin; V. Y. Panchenko

doi:10.3103/S1062873817070127

Exogenous iron redistribution between brain and liver after administering ⁵⁷Fe₃O₄ ferrofluid to a rat brain ventricle

R. R. Gabbasov^*, V. M. Cherepanov, M. A. Chuev, I. N. Mishchenko, D. M. Polikarpov, N. A. Loginova, E. V. Loseva, M. P. Nikitin, V. Y. Panchenko

^*Corresponding author for this work

Faculty of Medicine, Health and Human Sciences

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

The natural excretion of ⁵⁷Fe enriched magnetic nanoparticles from a rat’s brain through its blood–brain barrier is studied. Dextran-coated iron oxide nanoparticles are transcranially injected into the rat’s brain ventricle. The injected nanoparticles undergo biotransformation into iron-containing proteins distributed over the brain tissues, while the exogenous iron transported from the brain to other organs is eliminated from the body over time.

Original language	English
Pages (from-to)	788-792
Number of pages	5
Journal	Bulletin of the Russian Academy of Sciences: Physics
Volume	81
Issue number	7
DOIs	https://doi.org/10.3103/S1062873817070127
Publication status	Published - 1 Jul 2017

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Gabbasov, R. R., Cherepanov, V. M., Chuev, M. A., Mishchenko, I. N., Polikarpov, D. M., Loginova, N. A., Loseva, E. V., Nikitin, M. P., & Panchenko, V. Y. (2017). Exogenous iron redistribution between brain and liver after administering ⁵⁷Fe₃O₄ ferrofluid to a rat brain ventricle. Bulletin of the Russian Academy of Sciences: Physics, 81(7), 788-792. https://doi.org/10.3103/S1062873817070127

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title = "Exogenous iron redistribution between brain and liver after administering 57Fe3O4 ferrofluid to a rat brain ventricle",

abstract = "The natural excretion of 57Fe enriched magnetic nanoparticles from a rat{\textquoteright}s brain through its blood–brain barrier is studied. Dextran-coated iron oxide nanoparticles are transcranially injected into the rat{\textquoteright}s brain ventricle. The injected nanoparticles undergo biotransformation into iron-containing proteins distributed over the brain tissues, while the exogenous iron transported from the brain to other organs is eliminated from the body over time.",

author = "Gabbasov, {R. R.} and Cherepanov, {V. M.} and Chuev, {M. A.} and Mishchenko, {I. N.} and Polikarpov, {D. M.} and Loginova, {N. A.} and Loseva, {E. V.} and Nikitin, {M. P.} and Panchenko, {V. Y.}",

year = "2017",

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doi = "10.3103/S1062873817070127",

language = "English",

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Gabbasov, RR, Cherepanov, VM, Chuev, MA, Mishchenko, IN, Polikarpov, DM, Loginova, NA, Loseva, EV, Nikitin, MP & Panchenko, VY 2017, 'Exogenous iron redistribution between brain and liver after administering ⁵⁷Fe₃O₄ ferrofluid to a rat brain ventricle', Bulletin of the Russian Academy of Sciences: Physics, vol. 81, no. 7, pp. 788-792. https://doi.org/10.3103/S1062873817070127

TY - JOUR

T1 - Exogenous iron redistribution between brain and liver after administering 57Fe3O4 ferrofluid to a rat brain ventricle

AU - Gabbasov, R. R.

AU - Cherepanov, V. M.

AU - Chuev, M. A.

AU - Mishchenko, I. N.

AU - Polikarpov, D. M.

AU - Loginova, N. A.

AU - Loseva, E. V.

AU - Nikitin, M. P.

AU - Panchenko, V. Y.

PY - 2017/7/1

Y1 - 2017/7/1

N2 - The natural excretion of 57Fe enriched magnetic nanoparticles from a rat’s brain through its blood–brain barrier is studied. Dextran-coated iron oxide nanoparticles are transcranially injected into the rat’s brain ventricle. The injected nanoparticles undergo biotransformation into iron-containing proteins distributed over the brain tissues, while the exogenous iron transported from the brain to other organs is eliminated from the body over time.

AB - The natural excretion of 57Fe enriched magnetic nanoparticles from a rat’s brain through its blood–brain barrier is studied. Dextran-coated iron oxide nanoparticles are transcranially injected into the rat’s brain ventricle. The injected nanoparticles undergo biotransformation into iron-containing proteins distributed over the brain tissues, while the exogenous iron transported from the brain to other organs is eliminated from the body over time.

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SN - 1062-8738

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ER -

Exogenous iron redistribution between brain and liver after administering ⁵⁷Fe₃O₄ ferrofluid to a rat brain ventricle

Abstract

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