Experimental and theoretical tools to elucidate the binding mechanisms of solid-binding peptides

Rachit Bansal, Andrew Care, Megan S. Lord, Tiffany R. Walsh, Anwar Sunna

Research output: Contribution to journalReview articleResearchpeer-review

Abstract

The interactions between biomolecules and solid surfaces play an important role in designing new materials and applications which mimic nature. Recently, solid-binding peptides (SBPs) have emerged as potential molecular building blocks in nanobiotechnology. SBPs exhibit high selectivity and binding affinity towards a wide range of inorganic and organic materials. Although these peptides have been widely used in various applications, there is a need to understand the interaction mechanism between the peptide and its material substrate, which is challenging both experimentally and theoretically. This review describes the main characterisation techniques currently available to study SBP-surface interactions and their contribution to gain a better insight for designing new peptides for tailored binding.

LanguageEnglish
Pages9-18
Number of pages10
JournalNew Biotechnology
Volume52
DOIs
Publication statusPublished - 25 Sep 2019

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Peptides
Nanobiotechnology
Biomolecules
Substrates

Cite this

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Experimental and theoretical tools to elucidate the binding mechanisms of solid-binding peptides. / Bansal, Rachit; Care, Andrew; Lord, Megan S.; Walsh, Tiffany R.; Sunna, Anwar.

In: New Biotechnology, Vol. 52, 25.09.2019, p. 9-18.

Research output: Contribution to journalReview articleResearchpeer-review

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