Expert consensus document on arterial stiffness: Methodological issues and clinical applications

Stephane Laurent*, John Cockcroft, Luc Van Bortel, Pierre Boutouyrie, Cristina Giannattasio, Daniel Hayoz, Bruno Pannier, Charalambos Vlachopoulos, Ian Wilkinson, Harry Struijker-Boudier

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

4836 Citations (Scopus)


In recent years, great emphasis has been placed on the role of arterial stiffness in the development of cardiovascular diseases. Indeed, the assessment of arterial stiffness is increasingly used in the clinical assessment of patients. Although several papers have previously addressed the methodological issues concerning the various indices of arterial stiffness currently available, and their clinical applications, clinicians and researchers still report difficulties in selecting the most appropriate methodology for their specific use. This paper summarizes the proceedings of several meetings of the European Network for Non-invasive Investigation of Large Arteries and is aimed at providing an updated and practical overview of the most relevant methodological aspects and clinical applications in this area.

Original languageEnglish
Pages (from-to)2588-2605
Number of pages18
JournalEuropean Heart Journal
Issue number21
Publication statusPublished - Nov 2006
Externally publishedYes


  • Arterial stiffness
  • Artery
  • Cardiovascular events
  • Haemodynamics
  • Pathophysiology
  • Prognosis


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