Fabrication and characterization of a multiwall carbon nanotube needle biosensor

Yeo Heung Yun*, Adam Bange, Vesselin N. Shanov, William R. Heineman, H. Brian Halsall, Zhongyun Dong, Abdul Jazieh, Yi Tu, Danny Wong, Sarah Pixley, Michael Behbehani, Mark J. Schulz

*Corresponding author for this work

    Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionpeer-review

    2 Citations (Scopus)
    18 Downloads (Pure)


    A nanotube electronic needle biosensor was developed to provide fast, low cost, accurate detection of biomolecules. The sensor was formed by synthesizing highly aligned multi-wall carbon nanotube arrays. Nanotube bundles from the array were welded onto the tips of tungsten needles using a microscope. The needles were then encased in glass and a polymer coating. Cyclic voltammetry (CV) for the respective reduction of 6 mM K3Fe(CN)6 in a 1.0 M KNO3 was performed to examine the redox behavior of the nanotube needle. The CV results showed a steady-state response attributable to radial diffusion with a high steady-state current density. An amperometric sensor was then developed for glucose detection by physical attachment of glucose oxidase on the nanotube needle. A label-free immunosensor based on electrochemical impedance spectroscopy was also formed. The nanotube needle amperometric have good sensitivity with a low detection limit, and the possibility exists to keep decreasing the size of the needle to increase the sensitivity.

    Original languageEnglish
    Title of host publication2006 6th IEEE Conference on Nanotechnology, IEEE-NANO 2006
    Place of PublicationPiscataway, NJ
    PublisherInstitute of Electrical and Electronics Engineers (IEEE)
    Number of pages4
    ISBN (Print)1424400783, 9781424400782
    Publication statusPublished - 2006
    Event2006 6th IEEE Conference on Nanotechnology, IEEE-NANO 2006 - Cincinnati, OH, United States
    Duration: 17 Jun 200620 Jun 2006


    Other2006 6th IEEE Conference on Nanotechnology, IEEE-NANO 2006
    Country/TerritoryUnited States
    CityCincinnati, OH

    Bibliographical note

    Copyright 2006 IEEE. Reprinted from 2006 Sixth Conference on Nanotechnology : Westin Hotel, Cincinnati, Ohio, USA, 17-20 July, 2006. This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Macquarie University’s products or services. Internal or personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution must be obtained from the IEEE by writing to pubs-permissions@ieee.org. By choosing to view this document, you agree to all provisions of the copyright laws protecting it.


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