TY - GEN
T1 - Fabrication and characterization of a multiwall carbon nanotube needle biosensor
AU - Yun, Yeo Heung
AU - Bange, Adam
AU - Shanov, Vesselin N.
AU - Heineman, William R.
AU - Brian Halsall, H.
AU - Dong, Zhongyun
AU - Jazieh, Abdul
AU - Tu, Yi
AU - Wong, Danny
AU - Pixley, Sarah
AU - Behbehani, Michael
AU - Schulz, Mark J.
N1 - Copyright 2006 IEEE. Reprinted from 2006 Sixth Conference on Nanotechnology : Westin Hotel, Cincinnati, Ohio, USA, 17-20 July, 2006. This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Macquarie University’s products or services. Internal or personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution must be obtained from the IEEE by writing to [email protected]. By choosing to view this document, you agree to all provisions of the copyright laws protecting it.
PY - 2006
Y1 - 2006
N2 - A nanotube electronic needle biosensor was developed to provide fast, low cost, accurate detection of biomolecules. The sensor was formed by synthesizing highly aligned multi-wall carbon nanotube arrays. Nanotube bundles from the array were welded onto the tips of tungsten needles using a microscope. The needles were then encased in glass and a polymer coating. Cyclic voltammetry (CV) for the respective reduction of 6 mM K3Fe(CN)6 in a 1.0 M KNO3 was performed to examine the redox behavior of the nanotube needle. The CV results showed a steady-state response attributable to radial diffusion with a high steady-state current density. An amperometric sensor was then developed for glucose detection by physical attachment of glucose oxidase on the nanotube needle. A label-free immunosensor based on electrochemical impedance spectroscopy was also formed. The nanotube needle amperometric have good sensitivity with a low detection limit, and the possibility exists to keep decreasing the size of the needle to increase the sensitivity.
AB - A nanotube electronic needle biosensor was developed to provide fast, low cost, accurate detection of biomolecules. The sensor was formed by synthesizing highly aligned multi-wall carbon nanotube arrays. Nanotube bundles from the array were welded onto the tips of tungsten needles using a microscope. The needles were then encased in glass and a polymer coating. Cyclic voltammetry (CV) for the respective reduction of 6 mM K3Fe(CN)6 in a 1.0 M KNO3 was performed to examine the redox behavior of the nanotube needle. The CV results showed a steady-state response attributable to radial diffusion with a high steady-state current density. An amperometric sensor was then developed for glucose detection by physical attachment of glucose oxidase on the nanotube needle. A label-free immunosensor based on electrochemical impedance spectroscopy was also formed. The nanotube needle amperometric have good sensitivity with a low detection limit, and the possibility exists to keep decreasing the size of the needle to increase the sensitivity.
UR - http://www.scopus.com/inward/record.url?scp=42549139788&partnerID=8YFLogxK
M3 - Conference proceeding contribution
AN - SCOPUS:42549139788
SN - 1424400783
SN - 9781424400782
VL - 1
SP - 280
EP - 283
BT - 2006 6th IEEE Conference on Nanotechnology, IEEE-NANO 2006
PB - Institute of Electrical and Electronics Engineers (IEEE)
CY - Piscataway, NJ
T2 - 2006 6th IEEE Conference on Nanotechnology, IEEE-NANO 2006
Y2 - 17 June 2006 through 20 June 2006
ER -