Failure of normal glycaemic regulation in a patient with severe hypothermia

Robert N. C. Pfeifer*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


This report describes the case of an 88-year-old non-diabetic female who presented to the emergency department following a presumed hypoglycaemic collapse due to self-neglect. Subsequent rewarming and resuscitation demonstrated a number of the significant consequences of severe hypothermia, including apparent secondary impairment of glycaemic autoregulation. The phenomenon of reversible inhibition of insulin secretion due to severe hypothermia has been documented previously in the field of cardiac surgery. The hyperglycaemia was not treated with any antihyperglycaemic agent, and her recovery was uneventful. Subsequent blood sugar level monitoring was normal. If insulin is administered to the hypothermic patient, intensive monitoring of blood glucose is essential due to the increase in endogenous insulin secretion on rewarming.

Original languageEnglish
Pages (from-to)139-142
Number of pages4
Issue number1
Publication statusPublished - Jan 2006
Externally publishedYes

Bibliographical note

Erratum can be found in Resuscitation, Volume 80(5), 610,


  • hyperglycaemia
  • hypoglycaemia
  • hypothermia


Dive into the research topics of 'Failure of normal glycaemic regulation in a patient with severe hypothermia'. Together they form a unique fingerprint.

Cite this