First encounter

How pathogens compromise epithelial transport

Karl Kunzelmann*, Brendan McMorran

*Corresponding author for this work

Research output: Contribution to journalReview article

14 Citations (Scopus)

Abstract

Pathogenic organisms trigger numerous signaling pathways that ultimately lead to drastic changes in physiological functions. Apart from altering structure and function of the epithelial tight junction barrier and activating inflammatory cascades, they induce changes in fluid and electrolyte transport. Pathogens do so by activating or by inhibiting ion channels and transporters, and the result might be to their benefit or to their disadvantage.

Original languageEnglish
Pages (from-to)240-244
Number of pages5
JournalPhysiology
Volume19
Issue number5
Publication statusPublished - Oct 2004

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Kunzelmann, K., & McMorran, B. (2004). First encounter: How pathogens compromise epithelial transport. Physiology, 19(5), 240-244.