First line of defence: skin microbiota may protect anurans from infective larval lungworms

Keith Christian; Richard Shine; Kimberley A. Day; Mirjam Kaestli; Karen Gibb; Catherine M. Shilton; Gregory P. Brown

doi:10.1016/j.ijppaw.2021.02.014

First line of defence: skin microbiota may protect anurans from infective larval lungworms

Keith Christian, Richard Shine, Kimberley A. Day, Mirjam Kaestli, Karen Gibb, Catherine M. Shilton, Gregory P. Brown

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

41 Downloads (Pure)

Abstract

Functional roles of the rich microbiota of the skin are not fully understood, but include protection against microbial diseases and other environmental challenges. In experimental studies, we show that reducing the microbiota from cane toad (Rhinella marina) skin by gently wiping with absorptive gauze resulted in threefold higher rates of infection by lungworms (Rhabdias pseudosphaerocephala) following standardised exposure to infective skin-penetrating larvae. Higher concentrations of microbial DNA were associated with lower rates of lungworm entry. Our data suggest that microbial activity on the anuran skin comprises an important line of defence against attack by macroparasites as well as by fungi and other microbes.

Original language	English
Pages (from-to)	185-189
Number of pages	5
Journal	International Journal for Parasitology: Parasites and Wildlife
Volume	14
DOIs	https://doi.org/10.1016/j.ijppaw.2021.02.014
Publication status	Published - Apr 2021

Bibliographical note

Copyright the Author(s) 2021. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Keywords

Host-parasite
Microbiota
Pathogen
Rhabdias pseudosphaerocephala
Rhinella marina

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10.1016/j.ijppaw.2021.02.014

Publisher version (open access)Final published version, 3.16 MBLicence: CC BY-NC-ND

Cite this

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title = "First line of defence: skin microbiota may protect anurans from infective larval lungworms",

abstract = "Functional roles of the rich microbiota of the skin are not fully understood, but include protection against microbial diseases and other environmental challenges. In experimental studies, we show that reducing the microbiota from cane toad (Rhinella marina) skin by gently wiping with absorptive gauze resulted in threefold higher rates of infection by lungworms (Rhabdias pseudosphaerocephala) following standardised exposure to infective skin-penetrating larvae. Higher concentrations of microbial DNA were associated with lower rates of lungworm entry. Our data suggest that microbial activity on the anuran skin comprises an important line of defence against attack by macroparasites as well as by fungi and other microbes.",

keywords = "Host-parasite, Microbiota, Pathogen, Rhabdias pseudosphaerocephala, Rhinella marina",

author = "Keith Christian and Richard Shine and Day, {Kimberley A.} and Mirjam Kaestli and Karen Gibb and Shilton, {Catherine M.} and Brown, {Gregory P.}",

note = "Copyright the Author(s) 2021. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher. ",

year = "2021",

month = apr,

doi = "10.1016/j.ijppaw.2021.02.014",

language = "English",

volume = "14",

pages = "185--189",

journal = "International Journal for Parasitology: Parasites and Wildlife",

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T1 - First line of defence

T2 - skin microbiota may protect anurans from infective larval lungworms

AU - Christian, Keith

AU - Shine, Richard

AU - Day, Kimberley A.

AU - Kaestli, Mirjam

AU - Gibb, Karen

AU - Shilton, Catherine M.

AU - Brown, Gregory P.

N1 - Copyright the Author(s) 2021. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

PY - 2021/4

Y1 - 2021/4

N2 - Functional roles of the rich microbiota of the skin are not fully understood, but include protection against microbial diseases and other environmental challenges. In experimental studies, we show that reducing the microbiota from cane toad (Rhinella marina) skin by gently wiping with absorptive gauze resulted in threefold higher rates of infection by lungworms (Rhabdias pseudosphaerocephala) following standardised exposure to infective skin-penetrating larvae. Higher concentrations of microbial DNA were associated with lower rates of lungworm entry. Our data suggest that microbial activity on the anuran skin comprises an important line of defence against attack by macroparasites as well as by fungi and other microbes.

AB - Functional roles of the rich microbiota of the skin are not fully understood, but include protection against microbial diseases and other environmental challenges. In experimental studies, we show that reducing the microbiota from cane toad (Rhinella marina) skin by gently wiping with absorptive gauze resulted in threefold higher rates of infection by lungworms (Rhabdias pseudosphaerocephala) following standardised exposure to infective skin-penetrating larvae. Higher concentrations of microbial DNA were associated with lower rates of lungworm entry. Our data suggest that microbial activity on the anuran skin comprises an important line of defence against attack by macroparasites as well as by fungi and other microbes.

KW - Host-parasite

KW - Microbiota

KW - Pathogen

KW - Rhabdias pseudosphaerocephala

KW - Rhinella marina

UR - http://purl.org/au-research/grants/arc/DP190100507

UR - http://purl.org/au-research/grants/arc/DP190102395

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U2 - 10.1016/j.ijppaw.2021.02.014

DO - 10.1016/j.ijppaw.2021.02.014

M3 - Article

C2 - 33898219

SN - 2213-2244

VL - 14

SP - 185

EP - 189

JO - International Journal for Parasitology: Parasites and Wildlife

JF - International Journal for Parasitology: Parasites and Wildlife

ER -

First line of defence: skin microbiota may protect anurans from infective larval lungworms

Abstract

Bibliographical note

Keywords

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The evolution of host-parasite interactions during a biological invasion

Cite this

First line of defence: skin microbiota may protect anurans from infective larval lungworms

Abstract

Bibliographical note

Keywords

Access to Document

Other files and links

Fingerprint

Projects

The evolution of host-parasite interactions during a biological invasion

Cite this