First-trimester exposure to tofacitinib in ulcerative colitis: a case report of a healthy newborn and literature review

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Abstract

Tofacitinib is contraindicated in pregnancy. We present a patient with ulcerative colitis on tofacitinib who had an unplanned pregnancy. Tofacitinib was ceased, switched to vedolizumab, and she gave birth to a healthy newborn at term. Case reports of reassuring outcomes provide real-world data that assists decision-making for future patients.

Original languageEnglish
Article numbere8764
Pages (from-to)1-4
Number of pages4
JournalClinical Case Reports
Volume12
Issue number4
DOIs
Publication statusPublished - Apr 2024

Bibliographical note

Copyright the Author(s) 2024. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Keywords

  • Janus kinase inhibitors
  • Case report
  • Inflammatory bowel diseases
  • Pregnancy
  • Tofacitinib
  • Ulcerative colitis

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