We discuss the assessment of age- and time-specific disease incidence rising prevalence data. A method is described for conveniently fitting a discrete-time multiplicative model, subject to positivity constraints, using the EM-algorithm. Together with smoothing, it allows essentially nonparametric assessment of incidence trends. The method is illustrated using previously analyzed data on toxoplasmosis.
- Cross-sectional data
- Incidence and prevalence
- Multiplicative age time models