Fixed or random effects meta-analysis?: Common methodological issues in systematic reviews of effectiveness

Catalin Tufanaru; Zachary Munn; Matthew Stephenson; Edoardo Aromataris

doi:10.1097/XEB.0000000000000065

Fixed or random effects meta-analysis? Common methodological issues in systematic reviews of effectiveness

Catalin Tufanaru^*, Zachary Munn, Matthew Stephenson, Edoardo Aromataris

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

749 Citations (Scopus)

Abstract

Systematic review aims to systematically identify, critically appraise, and summarize all relevant studies that match predefined criteria and answer predefined questions. The most common type of systematic review is that assessing the effectiveness of an intervention or therapy. In this article, we discuss some of the common methodological issues that arise when conducting systematic reviews and meta-analyses of effectiveness data, including issues related to study designs, meta-analysis, and the use and interpretation of effect sizes.

Original language	English
Pages (from-to)	196-207
Number of pages	12
Journal	International Journal of Evidence-Based Healthcare
Volume	13
Issue number	3
DOIs	https://doi.org/10.1097/XEB.0000000000000065
Publication status	Published - 1 Sept 2015
Externally published	Yes

Keywords

Effect size
Effectiveness
Fixed effects
Meta-analysis
Random effects
Systematic review

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10.1097/XEB.0000000000000065

Cite this

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KW - Random effects

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Fixed or random effects meta-analysis? Common methodological issues in systematic reviews of effectiveness

Abstract

Keywords

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