TY - JOUR
T1 - Frequency and predictors of psychological distress after a diagnosis of epilepsy
T2 - a community-based study
AU - Xu, Ying
AU - Hackett, Maree L.
AU - Glozier, Nick
AU - Nikpour, Armin
AU - Bleasel, Andrew
AU - Somerville, Ernest
AU - Lawson, John
AU - Jan, Stephen
AU - Hyde, Lorne
AU - Todd, Lisa
AU - Martiniuk, Alexandra
AU - Ireland, Carol
AU - Anderson, Craig S.
PY - 2017/10
Y1 - 2017/10
N2 - Objective The objective of the study was to determine the frequency and predictors of psychological distress after a diagnosis of epilepsy. Methods The Sydney Epilepsy Incidence Study to Measure Illness Consequences (SEISMIC) was a prospective, multicenter, community-based study of people of all ages with newly diagnosed epilepsy in Sydney, Australia. Analyses involved multivariate logistic regression and multinomial logit regression to identify predictors of psychological distress, assessed using the Hospital Anxiety and Depression Scale (HADS) and the Strengths and Difficulties Questionnaire (SDQ), as part of structured interviews. Results Psychological distress occurred in 33% (95% confidence interval [CI] 26 to 40%) and 24% (95% CI 18 to 31%) of 180 adults at baseline and 12 months, respectively, and 23% (95% CI 14 to 33%) of 77 children at both time points. Thirty adults and 7 children had distress at baseline who recovered at 12 months, while 15 adults and 7 children had new onset of distress during this period. History of psychiatric or behavioral disorder (for adults, odds ratio [OR] 6.82, 95% CI 3.08 to 15.10; for children, OR 28.85, 95% CI 2.88 to 288.60) and higher psychosocial disability (adults, OR 1.17, 95% CI 1.07 to 1.27) or lower family functioning (children, OR 1.80, 95% CI 1.08 to 3.02) were associated with psychological distress (C statistics 0.80 and 0.78). Conclusions Psychological distress is common and fluctuates in frequency after a diagnosis of epilepsy. Those with premorbid psychological, psychosocial, and family problems are at high risk of this adverse outcome.
AB - Objective The objective of the study was to determine the frequency and predictors of psychological distress after a diagnosis of epilepsy. Methods The Sydney Epilepsy Incidence Study to Measure Illness Consequences (SEISMIC) was a prospective, multicenter, community-based study of people of all ages with newly diagnosed epilepsy in Sydney, Australia. Analyses involved multivariate logistic regression and multinomial logit regression to identify predictors of psychological distress, assessed using the Hospital Anxiety and Depression Scale (HADS) and the Strengths and Difficulties Questionnaire (SDQ), as part of structured interviews. Results Psychological distress occurred in 33% (95% confidence interval [CI] 26 to 40%) and 24% (95% CI 18 to 31%) of 180 adults at baseline and 12 months, respectively, and 23% (95% CI 14 to 33%) of 77 children at both time points. Thirty adults and 7 children had distress at baseline who recovered at 12 months, while 15 adults and 7 children had new onset of distress during this period. History of psychiatric or behavioral disorder (for adults, odds ratio [OR] 6.82, 95% CI 3.08 to 15.10; for children, OR 28.85, 95% CI 2.88 to 288.60) and higher psychosocial disability (adults, OR 1.17, 95% CI 1.07 to 1.27) or lower family functioning (children, OR 1.80, 95% CI 1.08 to 3.02) were associated with psychological distress (C statistics 0.80 and 0.78). Conclusions Psychological distress is common and fluctuates in frequency after a diagnosis of epilepsy. Those with premorbid psychological, psychosocial, and family problems are at high risk of this adverse outcome.
KW - Anxiety
KW - Depression
KW - Epilepsy
KW - Family function
KW - Stigma
UR - http://www.scopus.com/inward/record.url?scp=85028712375&partnerID=8YFLogxK
U2 - 10.1016/j.yebeh.2017.07.044
DO - 10.1016/j.yebeh.2017.07.044
M3 - Article
C2 - 28881320
AN - SCOPUS:85028712375
SN - 1525-5050
VL - 75
SP - 190
EP - 195
JO - Epilepsy and Behavior
JF - Epilepsy and Behavior
ER -