Abstract
Microbial molecular biology has traditionally used very reductionist approaches; for example, find a gene of interest, clone it or knock it out and see if you can detect a phenotype. The genomics era has opened up the possibility of analysing microbes and communities at a systems level by combining igh-throughput experimental data from genomic, transcriptomic, proteomic and phenomic techniques. This parallels earlier reductionist approaches by going from DNA to RNA to protein to phenotype, albeit on a global rather than individual gene scale.
Original language | English |
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Pages (from-to) | 147-151 |
Number of pages | 5 |
Journal | Microbiology Australia |
Volume | 32 |
Issue number | 4 |
Publication status | Published - 2011 |