TY - JOUR
T1 - From virus to vaccine
T2 - developments using the simple eukaryote, Dictyostelium discoideum
AU - Emslie, Kerry R.
AU - Slade, Martin B.
AU - Williams, Keith L.
PY - 1995
Y1 - 1995
N2 - Mass vaccination campaigns against viral diseases, both human and animal, depend on the availability of cheap viral antigens. The eukaryote Dictyostelium discoideum has simple growth requirements and rapid growth rates and forms stable cell lines. These features, together with the possibility of secreting recombinant (glyco) proteins into a defined buffer, make the D. discoideum expression system an attractive option for producing economical recombinant subunit vaccines.
AB - Mass vaccination campaigns against viral diseases, both human and animal, depend on the availability of cheap viral antigens. The eukaryote Dictyostelium discoideum has simple growth requirements and rapid growth rates and forms stable cell lines. These features, together with the possibility of secreting recombinant (glyco) proteins into a defined buffer, make the D. discoideum expression system an attractive option for producing economical recombinant subunit vaccines.
UR - http://www.scopus.com/inward/record.url?scp=0028834863&partnerID=8YFLogxK
U2 - 10.1016/S0966-842X(00)89015-0
DO - 10.1016/S0966-842X(00)89015-0
M3 - Article
C2 - 8800841
AN - SCOPUS:0028834863
SN - 0966-842X
VL - 3
SP - 476
EP - 479
JO - Trends in Microbiology
JF - Trends in Microbiology
IS - 12
ER -