From virus to vaccine

developments using the simple eukaryote, Dictyostelium discoideum

Kerry R. Emslie*, Martin B. Slade, Keith L. Williams

*Corresponding author for this work

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Mass vaccination campaigns against viral diseases, both human and animal, depend on the availability of cheap viral antigens. The eukaryote Dictyostelium discoideum has simple growth requirements and rapid growth rates and forms stable cell lines. These features, together with the possibility of secreting recombinant (glyco) proteins into a defined buffer, make the D. discoideum expression system an attractive option for producing economical recombinant subunit vaccines.

Original languageEnglish
Pages (from-to)476-479
Number of pages4
JournalTrends in Microbiology
Volume3
Issue number12
DOIs
Publication statusPublished - 1995

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