Functionalized single-walled carbon nanohorns for electrochemical biosensing

Xiaoqing Liu, Haijuan Li, Fuan Wang, Shuyun Zhu, Yuling Wang, Guobao Xu*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

37 Citations (Scopus)

Abstract

Single-walled carbon nanohorns (SWNHs), distinguished by their high purity and distinct structure, were noncovalently functionalized with poly(sodium 4-styrenesulfonate). The functionalized SWNHs were characterized by scanning electron microscopy, atomic force microscopy, ultraviolet-visible spectroscopy, Fourier transform infrared spectroscopy, Raman spectroscopy, and thermogravimetry. Heme protein myoglobin was adsorbed onto surface of functionalized SWNHs to prepare electrochemical biosensor. Surface assembly process and direct electrochemistry of immobilized myoglobin were investigated by electrochemical impedance spectroscopy and cyclic voltammetry, respectively. The proposed biosensor exhibited good electrocatalysis to the reduction of hydrogen peroxide. The response was linear over the range 3-350μM with a detection limit of 0.5μM. Good reproducibility and stability of the biosensor were obtained toward hydrogen peroxide detection.

Original languageEnglish
Pages (from-to)2194-2199
Number of pages6
JournalBiosensors and Bioelectronics
Volume25
Issue number10
DOIs
Publication statusPublished - Jun 2010
Externally publishedYes

Keywords

  • Biosensors
  • Carbon nanohorns
  • Carbon nanotubes
  • Heme proteins
  • Noncovalent functionalization

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