Gallium scanning in the management of mediastinal Hodgkin's disease

B. R. Wylie, A. E. Southee, D. E. Joshua*, A. F. McLaughlin, J. Gibson, B. F. Hutton, J. G. Morris, H. Kronenberg

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    52 Citations (Scopus)

    Abstract

    Gallium‐67 scanning was performed pre‐ and post‐therapy in 25 patients with Hodgkin's disease and a mediastinal mass. At restaging after therapy, radiographs (or CT scans) did not predict the presence of active disease whereas gallium scans did with a high degree of accuracy. Gallium‐67 determined disease activity in those patients who had a residual mediastinal mass predicting outcome in 11 out of 12 patients; one had a late relapse at 7 years. In patients without a residual mass gallium scanning was again accurate, predicting outcome in 11 of 13 patients. Two patients with negative gallium scans but subsequent active disease were scanned too soon after chemotherapy. The results suggest that gallium scanning has an important role in the mangement of mediastinal Hodgkin's disease and is superior to all current methods of assessing disease activity irrespective of the presence of a residual mediastinal mass.

    Original languageEnglish
    Pages (from-to)344-347
    Number of pages4
    JournalEuropean Journal of Haematology
    Volume42
    Issue number4
    DOIs
    Publication statusPublished - 1989

    Keywords

    • gallium scanning
    • Hodgkin's disease
    • mediastinal

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