Gastrointentinal bleed with clopidogrel and aspirin

Vikas Kohli; Anupam Sibal; Sujit Choudhary; Raja Joshi

doi:10.1007/s12098-009-0264-1

Gastrointentinal bleed with clopidogrel and aspirin

Vikas Kohli^*, Anupam Sibal, Sujit Choudhary, Raja Joshi

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Anti-platelet drugs have been used to prevent thrombosis of systemic to pulmonary artery shunts. Aspirin has traditionally been used. Clopidogrel is being studied as an alternative and in combination with aspirin for shunt patients. We report a near fatal gastro-intestinal bleed in a patient with shunt and on aspirin and clopidogrel. This combination has been known to produce similar bleeds. The authors recommend caution in combining them. Prospective studies currently underway should evaluate this aspect of the antiplatelet drugs.

Original language	English
Pages (from-to)	101-102
Number of pages	2
Journal	Indian Journal of Pediatrics
Volume	77
Issue number	1
DOIs	https://doi.org/10.1007/s12098-009-0264-1
Publication status	Published - Jan 2010
Externally published	Yes

Keywords

Clopidogrel
Cyanotic CHD
GI bleed

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abstract = "Anti-platelet drugs have been used to prevent thrombosis of systemic to pulmonary artery shunts. Aspirin has traditionally been used. Clopidogrel is being studied as an alternative and in combination with aspirin for shunt patients. We report a near fatal gastro-intestinal bleed in a patient with shunt and on aspirin and clopidogrel. This combination has been known to produce similar bleeds. The authors recommend caution in combining them. Prospective studies currently underway should evaluate this aspect of the antiplatelet drugs.",

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author = "Vikas Kohli and Anupam Sibal and Sujit Choudhary and Raja Joshi",

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AU - Kohli, Vikas

AU - Sibal, Anupam

AU - Choudhary, Sujit

AU - Joshi, Raja

PY - 2010/1

Y1 - 2010/1

N2 - Anti-platelet drugs have been used to prevent thrombosis of systemic to pulmonary artery shunts. Aspirin has traditionally been used. Clopidogrel is being studied as an alternative and in combination with aspirin for shunt patients. We report a near fatal gastro-intestinal bleed in a patient with shunt and on aspirin and clopidogrel. This combination has been known to produce similar bleeds. The authors recommend caution in combining them. Prospective studies currently underway should evaluate this aspect of the antiplatelet drugs.

AB - Anti-platelet drugs have been used to prevent thrombosis of systemic to pulmonary artery shunts. Aspirin has traditionally been used. Clopidogrel is being studied as an alternative and in combination with aspirin for shunt patients. We report a near fatal gastro-intestinal bleed in a patient with shunt and on aspirin and clopidogrel. This combination has been known to produce similar bleeds. The authors recommend caution in combining them. Prospective studies currently underway should evaluate this aspect of the antiplatelet drugs.

KW - Clopidogrel

KW - Cyanotic CHD

KW - GI bleed

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ER -

Gastrointentinal bleed with clopidogrel and aspirin

Abstract

Keywords

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