Gated myocardial perfusion SPECT

180° versus 360° reconstruction

Janelle M. Wheat*, Geoffrey M. Currie

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Introduction: The impact of 180° myocardial perfusion SPECT reconstruction on decreasing resolution may also impact on LV volume and LVEF. The purpose of this project was to determine the relationship between 180° and 360° gated myocardial perfusion SPECT reconstruction for the LV volumes and LVEF determined by QGS analysis and to determine whether QGS software is robust to variations in reconstruction parameters. Methodology: Each of 50 gated SPECT data sets (25 rest and 25 stress) were reconstructed using both 180° and 360° filtered backprojection simultaneously and quantified with automated QGS software to determine the LVEF, end diastolic volume (EDV) and end systolic volume (ESV). Results: The mean LVEF for 180° reconstruction was 49.5% and 49.7% for 360° reconstruction. No statistically significant difference was noted between matched pairs (P = 0.51). The mean EDV for 180° reconstruction was 108.3 ml and 104.6 ml for 360° reconstruction. A statistically significant difference was noted between matched pairs (P = 0.0006). The mean ESV for 180° reconstruction was 58.9 ml and 56.7 ml for 360° reconstruction. Again a statistically significant difference was noted between matched pairs (P = 0.0031). Conclusion: The QGS determined LVEF is robust to variations in reconstruction strategy. If 360° data is acquired, QGS software is capable of performing reliable reconstruction.

Original languageEnglish
Pages (from-to)7-11
Number of pages5
JournalANZ Nuclear Medicine
Volume37
Issue number1
Publication statusPublished - Mar 2006

Keywords

  • EDV
  • ESV
  • Left ventricular function
  • LVEF
  • Quantification
  • Reproducibility

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