Gene Mapping

Kelly L. Williams

doi:10.1016/B978-0-12-809633-8.20233-1

Gene Mapping

Macquarie University Centre for Motor Neuron Disease Research

Research output: Chapter in Book/Report/Conference proceeding › Entry for encyclopedia/dictionary/reference book › peer-review

2 Citations (Scopus)

Abstract

Gene mapping is a powerful tool that allows geneticists to identify genes that cause Mendelian disease, pinpoint loci for beneficial traits, and to compile and refine reference genomes for any species. This field of research begun with the first identification of co-inheritance of traits, through to linkage analysis, accelerating with the Human Genome Project, and still applicable in the current age of next-generation sequencing. Gene mapping has proven to be a high yield technique with both clinical and agricultural benefits.

Original language	English
Title of host publication	Encyclopedia of bioinformatics and computational biology
Editors	Shoba Ranganathan, Michael Gribskov, Kenta Nakai, Christian Schönbach, Bruno Gaeta
Place of Publication	Oxford
Publisher	Academic Press
Pages	242-250
Number of pages	9
Volume	2
ISBN (Print)	9780128114322, 9780128114148
DOIs	https://doi.org/10.1016/B978-0-12-809633-8.20233-1
Publication status	Published - 2019

Keywords

Crossover
Gene
Genetic marker
Inheritance
Linkage
Loci
Lod score
Mendelian
Recombination

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10.1016/B978-0-12-809633-8.20233-1

Cite this

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AB - Gene mapping is a powerful tool that allows geneticists to identify genes that cause Mendelian disease, pinpoint loci for beneficial traits, and to compile and refine reference genomes for any species. This field of research begun with the first identification of co-inheritance of traits, through to linkage analysis, accelerating with the Human Genome Project, and still applicable in the current age of next-generation sequencing. Gene mapping has proven to be a high yield technique with both clinical and agricultural benefits.

KW - Crossover

KW - Gene

KW - Genetic marker

KW - Inheritance

KW - Linkage

KW - Loci

KW - Lod score

KW - Mendelian

KW - Recombination

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DO - 10.1016/B978-0-12-809633-8.20233-1

M3 - Entry for encyclopedia/dictionary/reference book

SN - 9780128114322

SN - 9780128114148

VL - 2

SP - 242

EP - 250

BT - Encyclopedia of bioinformatics and computational biology

A2 - Ranganathan, Shoba

A2 - Gribskov, Michael

A2 - Nakai, Kenta

A2 - Schönbach, Christian

A2 - Gaeta, Bruno

PB - Academic Press

CY - Oxford

ER -

Gene Mapping

Abstract

Keywords

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