Gene Mapping

Kelly L. Williams

doi:10.1016/B978-0-323-95502-7.00205-0

Gene Mapping

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Gene mapping is a powerful tool that allows geneticists to identify genes that cause Mendelian disease, pinpoint loci for beneficial traits, and to compile and refine reference genomes for any species. This field of research begun with the first identification of co-inheritance of traits, through to linkage analysis, accelerating with the Human Genome Project, and still applicable in the current age of next- and third-generation sequencing. Gene mapping has proven to be a high yield technique with both clinical and agricultural benefits.

Original language	English
Title of host publication	Encyclopedia of Bioinformatics and Computational Biology
Editors	Shoba Ranganathan, Mario Cannataro, Mohammad Asif Khan
Publisher	Elsevier
Pages	243-253
Number of pages	11
Volume	3
Edition	2nd
ISBN (Electronic)	9780323955034
ISBN (Print)	9780323955027
DOIs	https://doi.org/10.1016/B978-0-323-95502-7.00205-0
Publication status	Published - 21 Mar 2025

Keywords

Crossover
Gene
Genetic marker
Inheritance
Linkage
Loci
LOD score
Recombination

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10.1016/B978-0-323-95502-7.00205-0

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title = "Gene Mapping",

abstract = "Gene mapping is a powerful tool that allows geneticists to identify genes that cause Mendelian disease, pinpoint loci for beneficial traits, and to compile and refine reference genomes for any species. This field of research begun with the first identification of co-inheritance of traits, through to linkage analysis, accelerating with the Human Genome Project, and still applicable in the current age of next- and third-generation sequencing. Gene mapping has proven to be a high yield technique with both clinical and agricultural benefits.",

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AU - Williams, Kelly L.

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N2 - Gene mapping is a powerful tool that allows geneticists to identify genes that cause Mendelian disease, pinpoint loci for beneficial traits, and to compile and refine reference genomes for any species. This field of research begun with the first identification of co-inheritance of traits, through to linkage analysis, accelerating with the Human Genome Project, and still applicable in the current age of next- and third-generation sequencing. Gene mapping has proven to be a high yield technique with both clinical and agricultural benefits.

AB - Gene mapping is a powerful tool that allows geneticists to identify genes that cause Mendelian disease, pinpoint loci for beneficial traits, and to compile and refine reference genomes for any species. This field of research begun with the first identification of co-inheritance of traits, through to linkage analysis, accelerating with the Human Genome Project, and still applicable in the current age of next- and third-generation sequencing. Gene mapping has proven to be a high yield technique with both clinical and agricultural benefits.

KW - Crossover

KW - Gene

KW - Genetic marker

KW - Inheritance

KW - Linkage

KW - Loci

KW - LOD score

KW - Recombination

UR - https://www.scopus.com/pages/publications/105030220214

U2 - 10.1016/B978-0-323-95502-7.00205-0

DO - 10.1016/B978-0-323-95502-7.00205-0

M3 - Chapter

SN - 9780323955027

VL - 3

SP - 243

EP - 253

BT - Encyclopedia of Bioinformatics and Computational Biology

A2 - Ranganathan, Shoba

A2 - Cannataro, Mario

A2 - Khan, Mohammad Asif

PB - Elsevier

ER -

Gene Mapping

Abstract

Keywords

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