GENELOSS: A computer program for simulating the effects of population bottlenecks on genetic diversity

P. R. England, G. H. R. Osler

    Research output: Contribution to journalArticlepeer-review

    22 Citations (Scopus)

    Abstract

    In the absence of tractable theory for predicting how population bottlenecks of longer than one generation reduce allelic diversity, we wrote the program GENELOSS to simulate the effects of population bottlenecks on genetic variation at highly polymorphic loci such as microsatellites. GENELOSS describes the heterozygosity and allelic diversity remaining after each iteration and averages the results of up to 3000 iterations. Thirty loci with 30 alleles each can be specified. Bottlenecks of up to 1000 pairs can run for an unlimited number of generations. GENELOSS will be a useful tool for the study of bottleneck effects and conservation biology.
    Original languageEnglish
    Pages (from-to)111-113
    Number of pages3
    JournalMolecular Ecology Notes
    Volume1
    Issue number1-2
    DOIs
    Publication statusPublished - 2001

    Keywords

    • Allelic diversity
    • Computer simulation
    • Conservation genetics
    • Heterozygosity
    • Microsatellite
    • Population bottleneck

    Fingerprint

    Dive into the research topics of 'GENELOSS: A computer program for simulating the effects of population bottlenecks on genetic diversity'. Together they form a unique fingerprint.

    Cite this