Generalizable sample-efficient siamese autoencoder for tinnitus diagnosis in listeners with subjective tinnitus

Zhe Liu, Lina Yao*, Xianzhi Wang, Jessica J. M. Monaghan, Roland Schaette, Zihuai He, David McAlpine

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)
13 Downloads (Pure)


Electroencephalogram (EEG)-based neurofeedback has been widely studied for tinnitus therapy in recent years. Most existing research relies on experts' cognitive prediction, and studies based on machine learning and deep learning are either data-hungry or not well generalizable to new subjects. In this paper, we propose a robust, data-efficient model for distinguishing tinnitus from the healthy state based on EEG-based tinnitus neurofeedback. We propose trend descriptor, a feature extractor with lower fineness, to reduce the effect of electrode noises on EEG signals, and a siamese encoder-decoder network boosted in a supervised manner to learn accurate alignment and to acquire high-quality transferable mappings across subjects and EEG signal channels. Our experiments show the proposed method significantly outperforms state-of-the-art algorithms when analyzing subjects' EEG neurofeedback to 90dB and 100dB sound, achieving an accuracy of 91.67%-94.44% in predicting tinnitus and control subjects in a subject-independent setting. Our ablation studies on mixed subjects and parameters show the method's stability in performance.

Original languageEnglish
Pages (from-to)1452-1461
Number of pages10
JournalIEEE Transactions on Neural Systems and Rehabilitation Engineering
Publication statusPublished - 2021

Bibliographical note

Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.


  • EEG
  • subject-independent
  • siamese autoencoder
  • domain alignment
  • trend descriptor
  • tinnitus


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