Genetic analysis workshop III: Use of multidimensional scaling in chromosome mapping

J. Donald; E. Sturt; G. Der; K. McCusker

doi:10.1002/gepi.1370020216

Genetic analysis workshop III: Use of multidimensional scaling in chromosome mapping

J. Donald^*, E. Sturt, G. Der, K. McCusker

^*Corresponding author for this work

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1 Citation (Scopus)

Abstract

Two‐point methods were used throughout. Male and female lod scores were calculated using LIPED. Edwards' programs, ZLODS and OBM, were used for joint analysis of the lod scores. ZLODS estimates recombination fractions. OBM calculates the likelihood and estimates the map distances for a given ordering of loci. Since OBM will only analyze a specified ordering, multidimensional scaling was used as a general method for establishing linkage groups and likely orderings within them.

Original language	English
Pages (from-to)	207-209
Number of pages	3
Journal	Genetic Epidemiology
Volume	2
Issue number	2
DOIs	https://doi.org/10.1002/gepi.1370020216
Publication status	Published - 1985
Externally published	Yes

Keywords

chromosome mapping
linkage
multidimensional scaling

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10.1002/gepi.1370020216

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abstract = "Two‐point methods were used throughout. Male and female lod scores were calculated using LIPED. Edwards' programs, ZLODS and OBM, were used for joint analysis of the lod scores. ZLODS estimates recombination fractions. OBM calculates the likelihood and estimates the map distances for a given ordering of loci. Since OBM will only analyze a specified ordering, multidimensional scaling was used as a general method for establishing linkage groups and likely orderings within them.",

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author = "J. Donald and E. Sturt and G. Der and K. McCusker",

year = "1985",

doi = "10.1002/gepi.1370020216",

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AU - Donald, J.

AU - Sturt, E.

AU - Der, G.

AU - McCusker, K.

PY - 1985

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AB - Two‐point methods were used throughout. Male and female lod scores were calculated using LIPED. Edwards' programs, ZLODS and OBM, were used for joint analysis of the lod scores. ZLODS estimates recombination fractions. OBM calculates the likelihood and estimates the map distances for a given ordering of loci. Since OBM will only analyze a specified ordering, multidimensional scaling was used as a general method for establishing linkage groups and likely orderings within them.

KW - chromosome mapping

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KW - multidimensional scaling

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ER -

Genetic analysis workshop III: Use of multidimensional scaling in chromosome mapping

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Keywords

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