Genetic analysis workshop III

Use of multidimensional scaling in chromosome mapping

J. Donald*, E. Sturt, G. Der, K. McCusker

*Corresponding author for this work

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Two‐point methods were used throughout. Male and female lod scores were calculated using LIPED. Edwards' programs, ZLODS and OBM, were used for joint analysis of the lod scores. ZLODS estimates recombination fractions. OBM calculates the likelihood and estimates the map distances for a given ordering of loci. Since OBM will only analyze a specified ordering, multidimensional scaling was used as a general method for establishing linkage groups and likely orderings within them.

Original languageEnglish
Pages (from-to)207-209
Number of pages3
JournalGenetic Epidemiology
Volume2
Issue number2
DOIs
Publication statusPublished - 1985
Externally publishedYes

Keywords

  • chromosome mapping
  • linkage
  • multidimensional scaling

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