Genetically modified ruminal bacteria protect sheep from fluoroacetate poisoning

Keith Gregg; Brenton Hamdorf; Kerrin Henderson; Jan Kopecny; Cheryl Wong

Genetically modified ruminal bacteria protect sheep from fluoroacetate poisoning

Keith Gregg^*, Brenton Hamdorf, Kerrin Henderson, Jan Kopecny, Cheryl Wong

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

86 Citations (Scopus)

Abstract

Four strains of Butyrivibrio fibrisolvens, transformed with a gene encoding fluoroacetate dehalogenase, maintained a combined population of 10⁶ to 10⁷ cells ml^-1 in the rumens of test sheep. Five inoculated sheep showed markedly reduced toxicological symptoms after fluoroacetate poisoning when behavioral, physiological, and histological effects were compared with those of five uninoculated control sheep.

Original language	English
Pages (from-to)	3496-3498
Number of pages	3
Journal	Applied and Environmental Microbiology
Volume	64
Issue number	9
Publication status	Published - 1998
Externally published	Yes

Cite this

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title = "Genetically modified ruminal bacteria protect sheep from fluoroacetate poisoning",

abstract = "Four strains of Butyrivibrio fibrisolvens, transformed with a gene encoding fluoroacetate dehalogenase, maintained a combined population of 106 to 107 cells ml-1 in the rumens of test sheep. Five inoculated sheep showed markedly reduced toxicological symptoms after fluoroacetate poisoning when behavioral, physiological, and histological effects were compared with those of five uninoculated control sheep.",

author = "Keith Gregg and Brenton Hamdorf and Kerrin Henderson and Jan Kopecny and Cheryl Wong",

year = "1998",

language = "English",

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TY - JOUR

T1 - Genetically modified ruminal bacteria protect sheep from fluoroacetate poisoning

AU - Gregg, Keith

AU - Hamdorf, Brenton

AU - Henderson, Kerrin

AU - Kopecny, Jan

AU - Wong, Cheryl

PY - 1998

Y1 - 1998

N2 - Four strains of Butyrivibrio fibrisolvens, transformed with a gene encoding fluoroacetate dehalogenase, maintained a combined population of 106 to 107 cells ml-1 in the rumens of test sheep. Five inoculated sheep showed markedly reduced toxicological symptoms after fluoroacetate poisoning when behavioral, physiological, and histological effects were compared with those of five uninoculated control sheep.

AB - Four strains of Butyrivibrio fibrisolvens, transformed with a gene encoding fluoroacetate dehalogenase, maintained a combined population of 106 to 107 cells ml-1 in the rumens of test sheep. Five inoculated sheep showed markedly reduced toxicological symptoms after fluoroacetate poisoning when behavioral, physiological, and histological effects were compared with those of five uninoculated control sheep.

UR - http://www.scopus.com/inward/record.url?scp=0031664574&partnerID=8YFLogxK

M3 - Article

C2 - 9726903

AN - SCOPUS:0031664574

SN - 0099-2240

VL - 64

SP - 3496

EP - 3498

JO - Applied and Environmental Microbiology

JF - Applied and Environmental Microbiology

IS - 9

ER -

Genetically modified ruminal bacteria protect sheep from fluoroacetate poisoning

Abstract

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