Ghrelin: A GH-releasing, appetite-regulating gastric hormone

Joseph Di Michele; Fabio Rotondo; Kalman Kovacs; Antonio Di Ieva; Luis V. Syro; Eleanor Latta; Michael D. Cusimano

doi:10.3233/NIB-130051

Ghrelin: A GH-releasing, appetite-regulating gastric hormone

Joseph Di Michele, Fabio Rotondo, Kalman Kovacs^*, Antonio Di Ieva, Luis V. Syro, Eleanor Latta, Michael D. Cusimano

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Ghrelin is a hormone that stimulates growth hormone (GH) release, and regulates appetite and feeding habits. It is synthesized and expressed to varying degrees in several organs and neoplasms. Its presence has been reported in the gastrointestinal and respiratory tracts, endocrine organs, cardiovascular system, kidney and central nervous system. Ghrelin producing cells can be demonstrated in the stomach, intestines, pancreas, kidneys, brain, and pituitary. The present review summarizes findings regarding the function and regulation of ghrelin in different organs and in various diseases.

Original language	English
Pages (from-to)	51-65
Number of pages	15
Journal	Advances in Neuroimmune Biology
Volume	4
Issue number	2
DOIs	https://doi.org/10.3233/NIB-130051
Publication status	Published - 2013
Externally published	Yes

Keywords

Growth hormone
orphan receptor
stomach

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10.3233/NIB-130051

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title = "Ghrelin: A GH-releasing, appetite-regulating gastric hormone",

abstract = "Ghrelin is a hormone that stimulates growth hormone (GH) release, and regulates appetite and feeding habits. It is synthesized and expressed to varying degrees in several organs and neoplasms. Its presence has been reported in the gastrointestinal and respiratory tracts, endocrine organs, cardiovascular system, kidney and central nervous system. Ghrelin producing cells can be demonstrated in the stomach, intestines, pancreas, kidneys, brain, and pituitary. The present review summarizes findings regarding the function and regulation of ghrelin in different organs and in various diseases.",

keywords = "Growth hormone, orphan receptor, stomach",

author = "{Di Michele}, Joseph and Fabio Rotondo and Kalman Kovacs and {Di Ieva}, Antonio and Syro, {Luis V.} and Eleanor Latta and Cusimano, {Michael D.}",

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language = "English",

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AU - Di Michele, Joseph

AU - Rotondo, Fabio

AU - Kovacs, Kalman

AU - Di Ieva, Antonio

AU - Syro, Luis V.

AU - Latta, Eleanor

AU - Cusimano, Michael D.

PY - 2013

Y1 - 2013

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AB - Ghrelin is a hormone that stimulates growth hormone (GH) release, and regulates appetite and feeding habits. It is synthesized and expressed to varying degrees in several organs and neoplasms. Its presence has been reported in the gastrointestinal and respiratory tracts, endocrine organs, cardiovascular system, kidney and central nervous system. Ghrelin producing cells can be demonstrated in the stomach, intestines, pancreas, kidneys, brain, and pituitary. The present review summarizes findings regarding the function and regulation of ghrelin in different organs and in various diseases.

KW - Growth hormone

KW - orphan receptor

KW - stomach

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U2 - 10.3233/NIB-130051

DO - 10.3233/NIB-130051

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JO - Advances in Neuroimmune Biology

JF - Advances in Neuroimmune Biology

SN - 1878-948X

IS - 2

ER -

Ghrelin: A GH-releasing, appetite-regulating gastric hormone

Abstract

Keywords

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