GHSI emergency radionuclide bioassay laboratory network: summary of the second exercise

Chunsheng Li, Christine Bartizel, Paolo Battisti, Axel Böttger, Céline Bouvier, Antonio Capote-Cuellar, Zhanat Carr, Derek Hammond, Martina Hartmann, Tarja Heikkinen, Robert L Jones, Eunjoo Kim, Raymond Ko, Roberto Koga, Boris Kukhta, Lorna Mitchell, Ryan Morhard, Francois Paquet, Debora Quayle, Petr RulikBaki Sadi, Aleksanin Sergei, Inmaculada Sierra, Wanderson de Oliveira Sousa, Gyula Szabό

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

The Global Health Security Initiative (GHSI) established a laboratory network within the GHSI community to develop collective surge capacity for radionuclide bioassay in response to a radiological or nuclear emergency as a means of enhancing response capability, health outcomes and community resilience. GHSI partners conducted an exercise in collaboration with the WHO Radiation Emergency Medical Preparedness and Assistance Network and the IAEA Response and Assistance Network, to test the participating laboratories (18) for their capabilities in in vitro assay of biological samples, using a urine sample spiked with multiple high-risk radionuclides (90Sr, 106Ru, 137Cs, and 239Pu). Laboratories were required to submit their reports within 72 h following receipt of the sample, using a pre-formatted template, on the procedures, methods and techniques used to identify and quantify the radionuclides in the sample, as well as the bioassay results with a 95% confidence interval. All of the participating laboratories identified and measured all or some of the radionuclides in the sample. However, gaps were identified in both the procedures used to assay multiple radionuclides in one sample, as well as in the methods or techniques used to assay specific radionuclides in urine. Two-third of the participating laboratories had difficulties in determining all the radionuclides in the sample. Results from this exercise indicate that challenges remain with respect to ensuring that results are delivered in a timely, consistent and reliable manner to support medical interventions. Laboratories within the networks are encouraged to work together to develop and maintain collective capabilities and capacity for emergency bioassay, which is an important component of radiation emergency response.

Original languageEnglish
Pages (from-to)449-456
Number of pages8
JournalRadiation Protection Dosimetry
Volume174
Issue number4
Early online date29 Aug 2016
DOIs
Publication statusPublished - 2017
Externally publishedYes

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