TY - JOUR
T1 - GHSI emergency radionuclide bioassay laboratory network
T2 - summary of the second exercise
AU - Li, Chunsheng
AU - Bartizel, Christine
AU - Battisti, Paolo
AU - Böttger, Axel
AU - Bouvier, Céline
AU - Capote-Cuellar, Antonio
AU - Carr, Zhanat
AU - Hammond, Derek
AU - Hartmann, Martina
AU - Heikkinen, Tarja
AU - Jones, Robert L
AU - Kim, Eunjoo
AU - Ko, Raymond
AU - Koga, Roberto
AU - Kukhta, Boris
AU - Mitchell, Lorna
AU - Morhard, Ryan
AU - Paquet, Francois
AU - Quayle, Debora
AU - Rulik, Petr
AU - Sadi, Baki
AU - Sergei, Aleksanin
AU - Sierra, Inmaculada
AU - de Oliveira Sousa, Wanderson
AU - Szabό, Gyula
N1 - © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
PY - 2017
Y1 - 2017
N2 - The Global Health Security Initiative (GHSI) established a laboratory network within the GHSI community to develop collective surge capacity for radionuclide bioassay in response to a radiological or nuclear emergency as a means of enhancing response capability, health outcomes and community resilience. GHSI partners conducted an exercise in collaboration with the WHO Radiation Emergency Medical Preparedness and Assistance Network and the IAEA Response and Assistance Network, to test the participating laboratories (18) for their capabilities in in vitro assay of biological samples, using a urine sample spiked with multiple high-risk radionuclides (90Sr, 106Ru, 137Cs, and 239Pu). Laboratories were required to submit their reports within 72 h following receipt of the sample, using a pre-formatted template, on the procedures, methods and techniques used to identify and quantify the radionuclides in the sample, as well as the bioassay results with a 95% confidence interval. All of the participating laboratories identified and measured all or some of the radionuclides in the sample. However, gaps were identified in both the procedures used to assay multiple radionuclides in one sample, as well as in the methods or techniques used to assay specific radionuclides in urine. Two-third of the participating laboratories had difficulties in determining all the radionuclides in the sample. Results from this exercise indicate that challenges remain with respect to ensuring that results are delivered in a timely, consistent and reliable manner to support medical interventions. Laboratories within the networks are encouraged to work together to develop and maintain collective capabilities and capacity for emergency bioassay, which is an important component of radiation emergency response.
AB - The Global Health Security Initiative (GHSI) established a laboratory network within the GHSI community to develop collective surge capacity for radionuclide bioassay in response to a radiological or nuclear emergency as a means of enhancing response capability, health outcomes and community resilience. GHSI partners conducted an exercise in collaboration with the WHO Radiation Emergency Medical Preparedness and Assistance Network and the IAEA Response and Assistance Network, to test the participating laboratories (18) for their capabilities in in vitro assay of biological samples, using a urine sample spiked with multiple high-risk radionuclides (90Sr, 106Ru, 137Cs, and 239Pu). Laboratories were required to submit their reports within 72 h following receipt of the sample, using a pre-formatted template, on the procedures, methods and techniques used to identify and quantify the radionuclides in the sample, as well as the bioassay results with a 95% confidence interval. All of the participating laboratories identified and measured all or some of the radionuclides in the sample. However, gaps were identified in both the procedures used to assay multiple radionuclides in one sample, as well as in the methods or techniques used to assay specific radionuclides in urine. Two-third of the participating laboratories had difficulties in determining all the radionuclides in the sample. Results from this exercise indicate that challenges remain with respect to ensuring that results are delivered in a timely, consistent and reliable manner to support medical interventions. Laboratories within the networks are encouraged to work together to develop and maintain collective capabilities and capacity for emergency bioassay, which is an important component of radiation emergency response.
UR - http://www.scopus.com/inward/record.url?scp=85044238761&partnerID=8YFLogxK
U2 - 10.1093/rpd/ncw254
DO - 10.1093/rpd/ncw254
M3 - Article
C2 - 27574317
VL - 174
SP - 449
EP - 456
JO - Radiation Protection Dosimetry
JF - Radiation Protection Dosimetry
SN - 0144-8420
IS - 4
ER -