Global estimates on the number of people blind or visually impaired by diabetic retinopathy: a meta-analysis from 2000 to 2020

Vision Loss Expert Group of the Global Burden of Disease Study; the GBD 2019 Blindness and Vision Impairment Collaborators

doi:10.1038/s41433-024-03101-5

Global estimates on the number of people blind or visually impaired by diabetic retinopathy: a meta-analysis from 2000 to 2020

Vision Loss Expert Group of the Global Burden of Disease Study, the GBD 2019 Blindness and Vision Impairment Collaborators

Macquarie Medical School

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

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Abstract

Objectives: To estimate global and regional trends from 2000 to 2020 of the number of persons visually impaired by diabetic retinopathy and their proportion of the total number of vision-impaired individuals. Methods: Data from population-based studies on eye diseases between 1980 to 2018 were compiled. Meta-regression models were performed to estimate the prevalence of blindness (presenting visual acuity <3/60) and moderate or severe vision impairment (MSVI; <6/18 to ≥3/60) attributed to DR. The estimates, with 95% uncertainty intervals [UIs], were stratified by age, sex, year, and region. Results: In 2020, 1.07 million (95% UI: 0.76, 1.51) people were blind due to DR, with nearly 3.28 million (95% UI: 2.41, 4.34) experiencing MSVI. The GBD super-regions with the highest percentage of all DR-related blindness and MSVI were Latin America and the Caribbean (6.95% [95% UI: 5.08, 9.51]) and North Africa and the Middle East (2.12% [95% UI: 1.55, 2.79]), respectively. Between 2000 and 2020, changes in DR-related blindness and MSVI were greater among females than males, predominantly in the super-regions of South Asia (blindness) and Southeast Asia, East Asia, and Oceania (MSVI). Conclusions: Given the rapid global rise in diabetes and increased life expectancy, DR is anticipated to persist as a significant public health challenge. The findings emphasise the need for gender-specific interventions and region-specific DR healthcare policies to mitigate disparities and prevent avoidable blindness. This study contributes to the expanding body of literature on the burden of DR, highlighting the need for increased global attention and investment in this research area.

Original language	English
Pages (from-to)	2047-2057
Number of pages	11
Journal	Eye (Basingstoke)
Volume	38
Issue number	11
DOIs	https://doi.org/10.1038/s41433-024-03101-5
Publication status	Published - Aug 2024

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Copyright the Author(s) 2024. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

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10.1038/s41433-024-03101-5Licence: CC BY

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@article{a5e2e93d38514cf992fe63125dc64f49,

title = "Global estimates on the number of people blind or visually impaired by diabetic retinopathy: a meta-analysis from 2000 to 2020",

abstract = "Objectives: To estimate global and regional trends from 2000 to 2020 of the number of persons visually impaired by diabetic retinopathy and their proportion of the total number of vision-impaired individuals. Methods: Data from population-based studies on eye diseases between 1980 to 2018 were compiled. Meta-regression models were performed to estimate the prevalence of blindness (presenting visual acuity <3/60) and moderate or severe vision impairment (MSVI; <6/18 to ≥3/60) attributed to DR. The estimates, with 95% uncertainty intervals [UIs], were stratified by age, sex, year, and region. Results: In 2020, 1.07 million (95% UI: 0.76, 1.51) people were blind due to DR, with nearly 3.28 million (95% UI: 2.41, 4.34) experiencing MSVI. The GBD super-regions with the highest percentage of all DR-related blindness and MSVI were Latin America and the Caribbean (6.95% [95% UI: 5.08, 9.51]) and North Africa and the Middle East (2.12% [95% UI: 1.55, 2.79]), respectively. Between 2000 and 2020, changes in DR-related blindness and MSVI were greater among females than males, predominantly in the super-regions of South Asia (blindness) and Southeast Asia, East Asia, and Oceania (MSVI). Conclusions: Given the rapid global rise in diabetes and increased life expectancy, DR is anticipated to persist as a significant public health challenge. The findings emphasise the need for gender-specific interventions and region-specific DR healthcare policies to mitigate disparities and prevent avoidable blindness. This study contributes to the expanding body of literature on the burden of DR, highlighting the need for increased global attention and investment in this research area.",

author = "{Vision Loss Expert Group of the Global Burden of Disease Study} and Katie Curran and Tunde Peto and Jonas, {Jost B.} and Friedman, {David S.} and Kim, {Judy E.} and Leasher, {Janet L.} and Ian Tapply and Fernandes, {Arthur G.} and Cicinelli, {Maria Vittoria} and Alessandro Arrigo and Nicolas Leveziel and Serge Resnikoff and Taylor, {Hugh R.} and Tabassom Sedighi and Seth Flaxman and Bikbov, {Mukkharram M.} and Tasanee Braithwaite and Alain Bron and Ching-Yu Cheng and {Del Monte}, {Monte A.} and Ehrlich, {Joshua R.} and Furtado, {Jo{\~a}o M.} and Gus Gazzard and Hartnett, {M. Elizabeth} and Rim Kahloun and Kempen, {John H.} and Moncef Khairallah and Khanna, {Rohit C.} and Lansingh, {Van Charles} and Naidoo, {Kovin S.} and Vinay Nangia and Michal Nowak and Konrad Pesudovs and Pradeep Ramulu and Fotis Topouzis and Mitiadis Tsilimbaris and Wang, {Ya Xing} and Ningli Wang and Bourne, {Rupert R. A.} and {the GBD 2019 Blindness and Vision Impairment Collaborators} and Kim, {Judy E.} and Ahinkorah, {Bright Opoku} and Hamid Ahmadieh and Ayman Ahmed and Alfaar, {Ahmad Samir} and Louay Almidani and Hubert Amu and Sofia Androudi and Jalal Arabloo and Aravkin, {Aleksandr Y.} and Asemu, {Mulu Tiruneh} and Azzam, {Ahmed Y.} and Nayereh Baghcheghi and Freddie Bailey and Baran, {Mehmet Firat} and Mainak Bardhan and B{\"a}rnighausen, {Till Winfried} and Amadou Barrow and Pankaj Bhardwaj and Briant, {Paul Svitil} and Katrin Burkart and C{\'a}mera, {Luis Alberto} and Kaleb Coberly and Omid Dadras and Xiaochen Dai and Amin Dehghan and Demessa, {Berecha Hundessa} and Mengistie Diress and Do, {Thanh Chi} and Do, {Thao Huynh Phuong} and Dokova, {Klara Georgieva} and Duncan, {Bruce B.} and Michael Ekholuenetale and Muhammed Elhadi and Emamian, {Mohammad Hassan} and Mehdi Emamverdi and Hossein Farrokhpour and Ali Fatehizadeh and Desideri, {Lorenzo Ferro} and Mesfin Gebrehiwot and Fariba Ghassemi and Gudeta, {Mesay Dechasa} and Sapna Gupta and Gupta, {Veer Bala} and Gupta, {Vivek Kumar} and Hammond, {Billy Randall} and Mehdi Harorani and Hamidreza Hasani and Golnaz Heidari and Mehdi Hosseinzadeh and Huang, {John J.} and Islam, {Sheikh Mohammed Shariful} and Nilofer Javadi and Aida Jimenez-Corona and Mohammad Jokar and Joshua, {Charity Ehimwenma} and Vidya Kadashetti and Himal Kandel and Hengameh Kasraei and Kaur, {Rimple Jeet} and Sudarshan Khanal and Zahra Khorrami and Koohestani, {Hamid Reza} and Kewal Krishan and Lim, {Stephen S.} and {El Razek}, {Mohammed Magdy Abd} and Vahid Mansouri and Andrea Maugeri and Tomislav Mestrovic and Awoke Misganaw and Mokdad, {Ali H.} and Hamed Momeni-Moghaddam and Sara Momtazmanesh and Murray, {Christopher J. L.} and Hadush Negash and Osuagwu, {Uchechukwu Levi} and Shahina Pardhan and Jay Patel and Shrikant Pawar and Ionela-Roxana Petcu and Pham, {Hoang Tran} and Mohsen Pourazizi and Ibrahim Qattea and Mosiur Rahman and Umar Saeed and Amirhossein Sahebkar and Salehi, {Mohammad Amin} and Maryam Shayan and Aminu Shittu and Steinmetz, {Jaimie D.} and Yao Tan and Aristidis Tsatsakis and Muhammad Umair and Theo Vos and Hong Xiao and Yuyi You and Zhang, {Zhi Jiang} and Zhang, {Zhi Jiang} and Peng Zheng",

note = "Copyright the Author(s) 2024. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.",

year = "2024",

month = aug,

doi = "10.1038/s41433-024-03101-5",

language = "English",

volume = "38",

pages = "2047--2057",

journal = "Eye (Basingstoke)",

issn = "0950-222X",

publisher = "Springer, Springer Nature",

number = "11",

}

Global estimates on the number of people blind or visually impaired by diabetic retinopathy: a meta-analysis from 2000 to 2020. / Vision Loss Expert Group of the Global Burden of Disease Study; the GBD 2019 Blindness and Vision Impairment Collaborators.
In: Eye (Basingstoke), Vol. 38, No. 11, 08.2024, p. 2047-2057.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Global estimates on the number of people blind or visually impaired by diabetic retinopathy

T2 - a meta-analysis from 2000 to 2020

AU - Vision Loss Expert Group of the Global Burden of Disease Study

AU - Curran, Katie

AU - Peto, Tunde

AU - Jonas, Jost B.

AU - Friedman, David S.

AU - Kim, Judy E.

AU - Leasher, Janet L.

AU - Tapply, Ian

AU - Fernandes, Arthur G.

AU - Cicinelli, Maria Vittoria

AU - Arrigo, Alessandro

AU - Leveziel, Nicolas

AU - Resnikoff, Serge

AU - Taylor, Hugh R.

AU - Sedighi, Tabassom

AU - Flaxman, Seth

AU - Bikbov, Mukkharram M.

AU - Braithwaite, Tasanee

AU - Bron, Alain

AU - Cheng, Ching-Yu

AU - Del Monte, Monte A.

AU - Ehrlich, Joshua R.

AU - Furtado, João M.

AU - Gazzard, Gus

AU - Hartnett, M. Elizabeth

AU - Kahloun, Rim

AU - Kempen, John H.

AU - Khairallah, Moncef

AU - Khanna, Rohit C.

AU - Lansingh, Van Charles

AU - Naidoo, Kovin S.

AU - Nangia, Vinay

AU - Nowak, Michal

AU - Pesudovs, Konrad

AU - Ramulu, Pradeep

AU - Topouzis, Fotis

AU - Tsilimbaris, Mitiadis

AU - Wang, Ya Xing

AU - Wang, Ningli

AU - Bourne, Rupert R. A.

AU - the GBD 2019 Blindness and Vision Impairment Collaborators

AU - Kim, Judy E.

AU - Ahinkorah, Bright Opoku

AU - Ahmadieh, Hamid

AU - Ahmed, Ayman

AU - Alfaar, Ahmad Samir

AU - Almidani, Louay

AU - Amu, Hubert

AU - Androudi, Sofia

AU - Arabloo, Jalal

AU - Aravkin, Aleksandr Y.

AU - Asemu, Mulu Tiruneh

AU - Azzam, Ahmed Y.

AU - Baghcheghi, Nayereh

AU - Bailey, Freddie

AU - Baran, Mehmet Firat

AU - Bardhan, Mainak

AU - Bärnighausen, Till Winfried

AU - Barrow, Amadou

AU - Bhardwaj, Pankaj

AU - Briant, Paul Svitil

AU - Burkart, Katrin

AU - Cámera, Luis Alberto

AU - Coberly, Kaleb

AU - Dadras, Omid

AU - Dai, Xiaochen

AU - Dehghan, Amin

AU - Demessa, Berecha Hundessa

AU - Diress, Mengistie

AU - Do, Thanh Chi

AU - Do, Thao Huynh Phuong

AU - Dokova, Klara Georgieva

AU - Duncan, Bruce B.

AU - Ekholuenetale, Michael

AU - Elhadi, Muhammed

AU - Emamian, Mohammad Hassan

AU - Emamverdi, Mehdi

AU - Farrokhpour, Hossein

AU - Fatehizadeh, Ali

AU - Desideri, Lorenzo Ferro

AU - Gebrehiwot, Mesfin

AU - Ghassemi, Fariba

AU - Gudeta, Mesay Dechasa

AU - Gupta, Sapna

AU - Gupta, Veer Bala

AU - Gupta, Vivek Kumar

AU - Hammond, Billy Randall

AU - Harorani, Mehdi

AU - Hasani, Hamidreza

AU - Heidari, Golnaz

AU - Hosseinzadeh, Mehdi

AU - Huang, John J.

AU - Islam, Sheikh Mohammed Shariful

AU - Javadi, Nilofer

AU - Jimenez-Corona, Aida

AU - Jokar, Mohammad

AU - Joshua, Charity Ehimwenma

AU - Kadashetti, Vidya

AU - Kandel, Himal

AU - Kasraei, Hengameh

AU - Kaur, Rimple Jeet

AU - Khanal, Sudarshan

AU - Khorrami, Zahra

AU - Koohestani, Hamid Reza

AU - Krishan, Kewal

AU - Lim, Stephen S.

AU - El Razek, Mohammed Magdy Abd

AU - Mansouri, Vahid

AU - Maugeri, Andrea

AU - Mestrovic, Tomislav

AU - Misganaw, Awoke

AU - Mokdad, Ali H.

AU - Momeni-Moghaddam, Hamed

AU - Momtazmanesh, Sara

AU - Murray, Christopher J. L.

AU - Negash, Hadush

AU - Osuagwu, Uchechukwu Levi

AU - Pardhan, Shahina

AU - Patel, Jay

AU - Pawar, Shrikant

AU - Petcu, Ionela-Roxana

AU - Pham, Hoang Tran

AU - Pourazizi, Mohsen

AU - Qattea, Ibrahim

AU - Rahman, Mosiur

AU - Saeed, Umar

AU - Sahebkar, Amirhossein

AU - Salehi, Mohammad Amin

AU - Shayan, Maryam

AU - Shittu, Aminu

AU - Steinmetz, Jaimie D.

AU - Tan, Yao

AU - Tsatsakis, Aristidis

AU - Umair, Muhammad

AU - Vos, Theo

AU - Xiao, Hong

AU - You, Yuyi

AU - Zhang, Zhi Jiang

AU - Zheng, Peng

N1 - Copyright the Author(s) 2024. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

PY - 2024/8

Y1 - 2024/8

N2 - Objectives: To estimate global and regional trends from 2000 to 2020 of the number of persons visually impaired by diabetic retinopathy and their proportion of the total number of vision-impaired individuals. Methods: Data from population-based studies on eye diseases between 1980 to 2018 were compiled. Meta-regression models were performed to estimate the prevalence of blindness (presenting visual acuity <3/60) and moderate or severe vision impairment (MSVI; <6/18 to ≥3/60) attributed to DR. The estimates, with 95% uncertainty intervals [UIs], were stratified by age, sex, year, and region. Results: In 2020, 1.07 million (95% UI: 0.76, 1.51) people were blind due to DR, with nearly 3.28 million (95% UI: 2.41, 4.34) experiencing MSVI. The GBD super-regions with the highest percentage of all DR-related blindness and MSVI were Latin America and the Caribbean (6.95% [95% UI: 5.08, 9.51]) and North Africa and the Middle East (2.12% [95% UI: 1.55, 2.79]), respectively. Between 2000 and 2020, changes in DR-related blindness and MSVI were greater among females than males, predominantly in the super-regions of South Asia (blindness) and Southeast Asia, East Asia, and Oceania (MSVI). Conclusions: Given the rapid global rise in diabetes and increased life expectancy, DR is anticipated to persist as a significant public health challenge. The findings emphasise the need for gender-specific interventions and region-specific DR healthcare policies to mitigate disparities and prevent avoidable blindness. This study contributes to the expanding body of literature on the burden of DR, highlighting the need for increased global attention and investment in this research area.

AB - Objectives: To estimate global and regional trends from 2000 to 2020 of the number of persons visually impaired by diabetic retinopathy and their proportion of the total number of vision-impaired individuals. Methods: Data from population-based studies on eye diseases between 1980 to 2018 were compiled. Meta-regression models were performed to estimate the prevalence of blindness (presenting visual acuity <3/60) and moderate or severe vision impairment (MSVI; <6/18 to ≥3/60) attributed to DR. The estimates, with 95% uncertainty intervals [UIs], were stratified by age, sex, year, and region. Results: In 2020, 1.07 million (95% UI: 0.76, 1.51) people were blind due to DR, with nearly 3.28 million (95% UI: 2.41, 4.34) experiencing MSVI. The GBD super-regions with the highest percentage of all DR-related blindness and MSVI were Latin America and the Caribbean (6.95% [95% UI: 5.08, 9.51]) and North Africa and the Middle East (2.12% [95% UI: 1.55, 2.79]), respectively. Between 2000 and 2020, changes in DR-related blindness and MSVI were greater among females than males, predominantly in the super-regions of South Asia (blindness) and Southeast Asia, East Asia, and Oceania (MSVI). Conclusions: Given the rapid global rise in diabetes and increased life expectancy, DR is anticipated to persist as a significant public health challenge. The findings emphasise the need for gender-specific interventions and region-specific DR healthcare policies to mitigate disparities and prevent avoidable blindness. This study contributes to the expanding body of literature on the burden of DR, highlighting the need for increased global attention and investment in this research area.

UR - http://www.scopus.com/inward/record.url?scp=85199813787&partnerID=8YFLogxK

U2 - 10.1038/s41433-024-03101-5

DO - 10.1038/s41433-024-03101-5

M3 - Article

C2 - 38937557

AN - SCOPUS:85199813787

SN - 0950-222X

VL - 38

SP - 2047

EP - 2057

JO - Eye (Basingstoke)

JF - Eye (Basingstoke)

IS - 11

ER -

Global estimates on the number of people blind or visually impaired by diabetic retinopathy: a meta-analysis from 2000 to 2020

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