TY - JOUR
T1 - Global estimates on the number of people blind or visually impaired by age-related macular degeneration
T2 - a meta-analysis from 2000 to 2020
AU - Vision Loss Expert Group of the Global Burden of Disease Study
AU - Furtado, João M.
AU - Jonas, Jost B.
AU - Tapply, Ian
AU - Fernandes, Arthur G.
AU - Cicinelli, Maria Vittoria
AU - Arrigo, Alessandro
AU - Leveziel, Nicolas
AU - Resnikoff, Serge
AU - Taylor, Hugh R.
AU - Sedighi, Tabassom
AU - Flaxman, Seth
AU - Battaglia Parodi, Maurizio
AU - Bikbov, Mukkharram M.
AU - Braithwaite, Tasanee
AU - Bron, Alain
AU - Cheng, Ching Yu
AU - Congdon, Nathan
AU - Del Monte, Monte A.
AU - Ehrlich, Joshua R.
AU - Fricke, Tim
AU - Friedman, David
AU - Gazzard, Gus
AU - Hartnett, M. Elizabeth
AU - Kahloun, Rim
AU - Kempen, John H.
AU - Khairallah, Moncef
AU - Khanna, Rohit C.
AU - Kim, Judy E.
AU - Lansingh, Van Charles
AU - Leasher, Janet
AU - Naidoo, Kovin S.
AU - Nangia, Vinay
AU - Nowak, Michal
AU - Pesudovs, Konrad
AU - Peto, Tunde
AU - Ramulu, Pradeep
AU - Topouzis, Fotis
AU - Tsilimbaris, Mitiadis
AU - Wang, Ya Xing
AU - Wang, Ningli
AU - Bourne, Rupert R. A.
AU - the GBD 2019 Blindness and Vision Impairment Collaborators
AU - Briant, Paul Svitil
AU - Vos, Theo
AU - Fischer, Florian
AU - Abate, Yohannes Habtegiorgis
AU - Abdollahi, Mohammad
AU - Adal, Tadele Girum Girum
AU - Addo, Isaac Yeboah
AU - Adhikari, Kishor
AU - Agarwal, Prerna
AU - Agodi, Antonella
AU - Agyemang-Duah, Williams
AU - Ahmad, Aqeel
AU - Ahmadieh, Hamid
AU - Ahmadzadeh, Hooman
AU - Alahdab, Fares
AU - Alfaar, Ahmad Samir
AU - Alhassan, Robert Kaba
AU - Ali, Syed Shujait Shujait
AU - Almidani, Louay
AU - Androudi, Sofia
AU - Anil, Abhishek
AU - Anyasodor, Anayochukwu Edward
AU - Arabloo, Jalal
AU - Ashemo, Mubarek Yesse
AU - Athari, Seyyed Shamsadin
AU - Atnafu, Desta Debalkie
AU - Atreya, Alok
AU - Ayalew, Melese Kitu
AU - Aynalem, Yared Asmare
AU - Aynalem, Zewdu Bishaw
AU - Azzam, Ahmed Y.
AU - Bagherieh, Sara
AU - Bai, Ruhai
AU - Barchitta, Martina
AU - Bardhan, Mainak
AU - Bärnighausen, Till Winfried
AU - Bayileyegn, Nebiyou Simegnew
AU - Bazvand, Fatemeh
AU - Begde, Ahmet
AU - Behnam, Babak
AU - Bhagavathula, Akshaya Srikanth
AU - Bhaskar, Sonu
AU - Bhatti, Gurjit Kaur
AU - Bhatti, Jasvinder Singh
AU - Bintoro, Bagas Suryo
AU - Birck, Marina G.
AU - Burkart, Katrin
AU - Bustanji, Yasser
AU - Caetano dos Santos, Florentino L.
AU - Carneiro, Vera L. A.
AU - Cenderadewi, Muthia
AU - Chattu, Vijay Kumar
AU - Chu, Dinh Toi
AU - Coberly, Kaleb
AU - Cruz-Martins, Natália
AU - Dadras, Omid
AU - Dai, Xiaochen
AU - Dascalu, Ana Maria
AU - Dashti, Mohsen
AU - Dastiridou, Anna
AU - Dastmardi, Maedeh
AU - Deng, Xinlei
AU - Dervenis, Nikolaos
AU - Devanbu, Vinoth Gnana Chellaiyan
AU - Diress, Mengistie
AU - Djalalinia, Shirin
AU - Ekholuenetale, Michael
AU - Ekundayo, Temitope Cyrus
AU - El Sayed, Iman
AU - Elhadi, Muhammed
AU - Emamverdi, Mehdi
AU - Emrie, Ambaw Abebaw
AU - Fagbamigbe, Adeniyi Francis
AU - Fahim, Ayesha
AU - Farooq, Umar
AU - Farrokhpour, Hossein
AU - Fatehizadeh, Ali
AU - Feizkhah, Alireza
AU - Ferro Desideri, Lorenzo
AU - Fetensa, Getahun
AU - Feyisa, Bikila Regassa
AU - Forouhari, Ali
AU - Foschi, Matteo
AU - Fowobaje, Kayode Raphael
AU - Gandhi, Aravind P.
AU - Gebi, Tilaye Gebru
AU - Gebregergis, Miglas W.
AU - Gebrehiwot, Mesfin
AU - Gebremariam, Brhane
AU - Gebremeskel, Gebreamlak Gebremedhn
AU - Gela, Yibeltal Yismaw
AU - Gesese, Molalegn Mesele
AU - Ghasemi Falavarjani, Khalil
AU - Ghassemi, Fariba
AU - Ghozy, Sherief
AU - Golechha, Mahaveer
AU - Goleij, Pouya
AU - Gupta, Sapna
AU - Gupta, Veer Bala
AU - Gupta, Vivek Kumar
AU - Haile, Teklehaimanot Gereziher
AU - Hailu, Semira Goitom
AU - Haj-Mirzaian, Arvin
AU - Halimi, Aram
AU - Hallaj, Shahin
AU - Hammond, Billy Randall
AU - Hasan, Ikramul
AU - Hasani, Hamidreza
AU - Hassanian-Moghaddam, Hossein
AU - Heidari-Foroozan, Mahsa
AU - Hong, Sung Hwi
AU - Hoogar, Praveen
AU - Hosseinzadeh, Mehdi
AU - Hu, Chengxi
AU - Huynh, Hong Han
AU - Immurana, Mustapha
AU - Iwu, Chidozie C. D.
AU - Jacob, Louis
AU - Jafarzadeh, Abdollah
AU - Jakovljevic, Mihajlo
AU - Jayaram, Shubha
AU - Jokar, Mohammad
AU - Joseph, Nitin
AU - Joshua, Charity Ehimwenma
AU - Kabito, Gebisa Guyasa
AU - Kalankesh, Laleh R.
AU - Kamath, Sagarika
AU - Kandel, Himal
AU - Karaye, Ibraheem M.
AU - Kasraei, Hengameh
AU - Kayode, Gbenga A.
AU - Kedir, Shemsu
AU - Khader, Yousef Saleh
AU - Khajuria, Himanshu
AU - Khatatbeh, Moawiah Mohammad
AU - Khatib, Mahalaqua Nazli
AU - Khorrami, Zahra
AU - Kim, Yun Jin
AU - Kisa, Adnan
AU - Kisa, Sezer
AU - Kosen, Soewarta
AU - Koyanagi, Ai
AU - Krishan, Kewal
AU - Lahariya, Chandrakant
AU - Laksono, Tri
AU - Lal, Dharmesh Kumar
AU - Le, Trang D. T.
AU - Lee, Munjae
AU - Lee, Seung Won
AU - Lee, Wei-Chen
AU - Lim, Stephen S.
AU - Liu, Xuefeng
AU - Mahmoudi, Alireza
AU - Mahmoudi, Razzagh
AU - Malhotra, Kashish
AU - Mansouri, Vahid
AU - Marzo, Roy Rillera
AU - Maugeri, Andrea
AU - McAlinden, Colm
AU - Mekene Meto, Tesfahun
AU - Mersha, Abera M.
AU - Mestrovic, Tomislav
AU - Mihretie, Ephrem Tesfaye
AU - Mirzaei, Mehdi
AU - Mithra, Prasanna
AU - Mohamed, Nouh Saad
AU - Mohammadi, Soheil
AU - Mohammed, Abdulwase
AU - Mokdad, Ali H.
AU - Molavi Vardanjani, Hossein
AU - Moni, Mohammad Ali
AU - Montazeri, Fateme
AU - Moradi, Maryam
AU - Mousavi, Parsa
AU - Muhamed, Ahmed Nuru
AU - Mulita, Admir
AU - Naik, Ganesh R.
AU - Nargus, Shumaila
AU - Natto, Zuhair S.
AU - Nayak, Biswa Prakash
AU - Negaresh, Mohammad
AU - Negash, Hadush
AU - Nejadghaderi, Seyed Aria
AU - Nguyen, Dang H.
AU - Nguyen, Hien Quang
AU - Nguyen, Phat Tuan
AU - Nguyen, Van Thanh
AU - Niazi, Robina Khan
AU - Noreen, Mamoona
AU - Nzoputam, Ogochukwu Janet
AU - Odetokun, Ismail A.
AU - Olagunju, Andrew T.
AU - Olatubi, Matthew Idowu
AU - Onwujekwe, Obinna E.
AU - Ordak, Michal
AU - Osuagwu, Uchechukwu Levi
AU - Otstavnov, Nikita
AU - Owolabi, Mayowa O.
AU - Padubidri, Jagadish Rao
AU - Panahi, Parsa
AU - Pandey, Ashok
AU - Pardhan, Shahina
AU - Patel, Jay
AU - Patthipati, Venkata Suresh
AU - Pawar, Shrikant
AU - Perianayagam, Arokiasamy
AU - Petcu, Ionela-Roxana
AU - Pham, Hoang Tran
AU - Qattea, Ibrahim
AU - Raghav, Pankaja Raghav
AU - Rahim, Fakher
AU - Rahimi-Movaghar, Vafa
AU - Rahman, Mohammad Hifz Ur
AU - Rahman, Mosiur
AU - Ramasubramani, Premkumar
AU - Rashid, Ahmed Mustafa
AU - Rauf, Annisa Utami
AU - Redwan, Elrashdy Moustafa Mohamed
AU - Rezaei, Nazila
AU - Roy, Priyanka
AU - Saadatian, Zahra
AU - Sabour, Siamak
AU - Saddik, Basema
AU - Saeed, Umar
AU - Safi, Sare
AU - Safi, Sher Zaman
AU - Saghazadeh, Amene
AU - Sharif-Askari, Fatemeh Saheb
AU - Sharif-Askari, Narjes Saheb
AU - Sahebkar, Amirhossein
AU - Sakshaug, Joseph W.
AU - Salahi, Saina
AU - Salahi, Sarvenaz
AU - Saleh, Mohamed A.
AU - Samodra, Yoseph Leonardo
AU - Samuel, Vijaya Paul
AU - Samy, Abdallah M.
AU - Saravanan, Aswini
AU - Sawhney, Monika
AU - Saylan, Mete
AU - Sediqi, Sayed Mansoor
AU - Selvaraj, Siddharthan
AU - Sethi, Yashendra
AU - Seylani, Allen
AU - Shah, Jaffer
AU - Shahid, Samiah
AU - Shahwan, Moyad Jamal
AU - Shaikh, Masood Ali
AU - Shamim, Muhammad Aaqib
AU - Shayan, Maryam
AU - Shigematsu, Mika
AU - Shittu, Aminu
AU - Shorofi, Seyed Afshin
AU - Siddig, Emmanuel Edwar
AU - Silva, Juan Carlos
AU - Singh, Jasvinder A.
AU - Singh, Paramdeep
AU - Skiadaresi, Eirini
AU - Sousa, Raul A. R. C.
AU - Sreeramareddy, Chandrashekhar T.
AU - Starodubov, Vladimir I.
AU - Taye, Birhan Tsegaw
AU - Ticoalu, Jansje Henny Vera
AU - Tsegay, Guesh Mebrahtom
AU - Ullah, Saif
AU - Umair, Muhammad
AU - Tahbaz, Sahel Valadan
AU - Wickramasinghe, Nuwan Darshana
AU - Wondimagegn, Guadie Sharew
AU - Yang, Lin
AU - Yigit, Arzu
AU - Yon, Dong Keon
AU - Yonemoto, Naohiro
AU - You, Yuyi
AU - Zastrozhin, Mikhail Sergeevich
AU - Zhao, Hanqing
AU - Zheng, Peng
AU - Ziafati, Makan
AU - Zielińska, Magdalena
AU - Steinmetz, Jaimie D.
N1 - Copyright the Author(s) 2024. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.
PY - 2024/8
Y1 - 2024/8
N2 - Background: We aimed to update estimates of global vision loss due to age-related macular degeneration (AMD). Methods: We did a systematic review and meta-analysis of population-based surveys of eye diseases from January, 1980, to October, 2018. We fitted hierarchical models to estimate the prevalence of moderate and severe vision impairment (MSVI; presenting visual acuity from <6/18 to 3/60) and blindness (< 3/60) caused by AMD, stratified by age, region, and year. Results: In 2020, 1.85 million (95%UI: 1.35 to 2.43 million) people were estimated to be blind due to AMD, and another 6.23 million (95%UI: 5.04 to 7.58) with MSVI globally. High-income countries had the highest number of individuals with AMD-related blindness (0.60 million people; 0.46 to 0.77). The crude prevalence of AMD-related blindness in 2020 (among those aged ≥ 50 years) was 0.10% (0.07 to 0.12) globally, and the region with the highest prevalence of AMD-related blindness was North Africa/Middle East (0.22%; 0.16 to 0.30). Age-standardized prevalence (using the GBD 2019 data) of AMD-related MSVI in people aged ≥ 50 years in 2020 was 0.34% (0.27 to 0.41) globally, and the region with the highest prevalence of AMD-related MSVI was also North Africa/Middle East (0.55%; 0.44 to 0.68). From 2000 to 2020, the estimated crude prevalence of AMD-related blindness decreased globally by 19.29%, while the prevalence of MSVI increased by 10.08%. Conclusions: The estimated increase in the number of individuals with AMD-related blindness and MSVI globally urges the creation of novel treatment modalities and the expansion of rehabilitation services.
AB - Background: We aimed to update estimates of global vision loss due to age-related macular degeneration (AMD). Methods: We did a systematic review and meta-analysis of population-based surveys of eye diseases from January, 1980, to October, 2018. We fitted hierarchical models to estimate the prevalence of moderate and severe vision impairment (MSVI; presenting visual acuity from <6/18 to 3/60) and blindness (< 3/60) caused by AMD, stratified by age, region, and year. Results: In 2020, 1.85 million (95%UI: 1.35 to 2.43 million) people were estimated to be blind due to AMD, and another 6.23 million (95%UI: 5.04 to 7.58) with MSVI globally. High-income countries had the highest number of individuals with AMD-related blindness (0.60 million people; 0.46 to 0.77). The crude prevalence of AMD-related blindness in 2020 (among those aged ≥ 50 years) was 0.10% (0.07 to 0.12) globally, and the region with the highest prevalence of AMD-related blindness was North Africa/Middle East (0.22%; 0.16 to 0.30). Age-standardized prevalence (using the GBD 2019 data) of AMD-related MSVI in people aged ≥ 50 years in 2020 was 0.34% (0.27 to 0.41) globally, and the region with the highest prevalence of AMD-related MSVI was also North Africa/Middle East (0.55%; 0.44 to 0.68). From 2000 to 2020, the estimated crude prevalence of AMD-related blindness decreased globally by 19.29%, while the prevalence of MSVI increased by 10.08%. Conclusions: The estimated increase in the number of individuals with AMD-related blindness and MSVI globally urges the creation of novel treatment modalities and the expansion of rehabilitation services.
UR - https://www.scopus.com/pages/publications/85199813397
U2 - 10.1038/s41433-024-03050-z
DO - 10.1038/s41433-024-03050-z
M3 - Article
C2 - 38965321
AN - SCOPUS:85199813397
SN - 0950-222X
VL - 38
SP - 2070
EP - 2082
JO - Eye (Basingstoke)
JF - Eye (Basingstoke)
IS - 11
ER -