Glycoinformatics

Matthew P. Campbell, Kiyoko F. Aoki-Kinoshita, Frederique Lisacek, William S. York, Nicolle H. Packer

Research output: Chapter in Book/Report/Conference proceedingTextbook contribution

Abstract

Previous chapters have described how glycans are not directly encoded by genes and that they are biosynthetically and structurally complex. The identity of each glycan in a biological sample must be identified using analytical methods to determine these diverse structural features. As a consequence, research aimed at understanding the biological roles and consequences of glycan structures depends on the availability of databases that allow these structures to be defined, archived, organized, searched, annotated, and linked to other databases with related genomic and proteomic information. This chapter describes the current status of collecting, organizing, and extending data from existing user-entered glycan structure and function databases.
Original languageEnglish
Title of host publicationEssentials of glycobiology
EditorsAjit Varki, Richard D. Cummings, Jeffrey D. Esko, Pamela Stanley, Gerald W. Hart, Markus Aebi, Alan G. Darvill, Taroh Kinoshita, Nicolle H. Packer, James H. Prestegard, Ronald L. Schnaar, Peter H. Seeberger
Place of PublicationCold Spring Harbor, New York
PublisherCold Spring Harbor Laboratory Press
Chapter52
Pages667-679
Number of pages13
Edition3rd
ISBN (Print)9781621821328
Publication statusPublished - 2017

Keywords

  • glycobiology
  • glycoinformatics

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