TY - JOUR
T1 - GlycoSuiteDB
T2 - A new curated relational database of glycoprotein glycan structures and their biological sources
AU - Cooper, Catherine A.
AU - Harrison, Mathew J.
AU - Wilkins, Marc R.
AU - Packer, Nicolle H.
PY - 2001/1/1
Y1 - 2001/1/1
N2 - GlycoSuiteDB is a relational database that curates information from the scientific literature on glycoprotein derived glycan structures, their biological sources, the references in which the glycan was described and the methods used to determine the glycan structure. To date, the database includes most published O-linked oligosaccharides from the last 50 years and most N-linked oligosaccharides that were published in the 1990s. For each structure, in formation is available concerning the glycan type, linkage and anomeric configuration, mass and composition. Detailed information is also provided on native and recombinant sources, including tissue and/or cell type, cell line, strain and disease state. Where known, the proteins to which the glycan structures are attached are reported, and cross-references to the SWISS-PROT/TrEMBL protein sequence databases are given if applicable. The GlycoSuiteDB annotations include literature references which are linked to PubMed, and detailed information on the methods used to determine each glycan structure are noted to help the user assess the quality of the structural assignment. GlycoSuiteDB has a user-friendly web interface which allows the researcher to query the database using monoisotopic or average mass, monosaccharide composition, glycosylation linkages (e.g. N- or O-linked), reducing terminal sugar, attached protein, taxonomy, tissue or cell type and GlycoSuiteDB accession number. Advanced queries using combinations of these parameters are also possible. GlycoSuiteDB can be accessed on the web at http://www.glycosuite.com.
AB - GlycoSuiteDB is a relational database that curates information from the scientific literature on glycoprotein derived glycan structures, their biological sources, the references in which the glycan was described and the methods used to determine the glycan structure. To date, the database includes most published O-linked oligosaccharides from the last 50 years and most N-linked oligosaccharides that were published in the 1990s. For each structure, in formation is available concerning the glycan type, linkage and anomeric configuration, mass and composition. Detailed information is also provided on native and recombinant sources, including tissue and/or cell type, cell line, strain and disease state. Where known, the proteins to which the glycan structures are attached are reported, and cross-references to the SWISS-PROT/TrEMBL protein sequence databases are given if applicable. The GlycoSuiteDB annotations include literature references which are linked to PubMed, and detailed information on the methods used to determine each glycan structure are noted to help the user assess the quality of the structural assignment. GlycoSuiteDB has a user-friendly web interface which allows the researcher to query the database using monoisotopic or average mass, monosaccharide composition, glycosylation linkages (e.g. N- or O-linked), reducing terminal sugar, attached protein, taxonomy, tissue or cell type and GlycoSuiteDB accession number. Advanced queries using combinations of these parameters are also possible. GlycoSuiteDB can be accessed on the web at http://www.glycosuite.com.
UR - http://www.scopus.com/inward/record.url?scp=0035170507&partnerID=8YFLogxK
U2 - 10.1093/nar/29.1.332
DO - 10.1093/nar/29.1.332
M3 - Article
C2 - 11125129
AN - SCOPUS:0035170507
SN - 0305-1048
VL - 29
SP - 332
EP - 335
JO - Nucleic Acids Research
JF - Nucleic Acids Research
IS - 1
ER -