GlycoViewer

A tool for visual summary and comparative analysis of the glycome

Hiren J. Joshi, Claus Wilhelm von der Lieth, Nicolle H. Packer, Marc R. Wilkins*

*Corresponding author for this work

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The GlycoViewer (http://www.systemsbiology.org.au/glycoviewer) is a web-based tool that can visualize, summarize and compare sets of glycan structures. Its input is a group of glycan structures; these can be entered as a list in IUPAC format or via a sugar structure builder. Its output is a detailed graphic, which summarizes all salient features of the glycans according to the shapes of the core structures, the nature and length of any chains, and the types of terminal epitopes. The tool can summarize up to hundreds of structures in a single figure. This allows unique, high-level views to be generated of glycans from one protein, from a cell, a tissue or a whole organism. Use of the tool is illustrated in the analysis of normal and diseaseassociated glycans from the human glycoproteome.

Original languageEnglish
Article numbergkq446
Pages (from-to)W667-W670
Number of pages4
JournalNucleic Acids Research
Volume38
Issue numberSUPPL. 2
DOIs
Publication statusPublished - 25 May 2010

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