Glycozylhydrazines, preparation, immobilization and reactions of: glycoprotein analysis and O-glycan removal

Michael Batley; Catherine Anne Cooper; Andrew Arthur Gooley; Warren Charles Kett; Nicolle Hannah Packer; Anthony Pisano; John William Redmond; Helen Joan Tweeddale; Keith Leslie Williams

Glycozylhydrazines, preparation, immobilization and reactions of: glycoprotein analysis and O-glycan removal

Michael Batley (Inventor), Catherine Anne Cooper (Inventor), Andrew Arthur Gooley (Inventor), Warren Charles Kett (Inventor), Nicolle Hannah Packer (Inventor), Anthony Pisano (Inventor), John William Redmond (Inventor), Helen Joan Tweeddale (Inventor), Keith Leslie Williams (Inventor)

Macquarie University

Research output: Patent

Abstract

The present invention consists in methods of preparing sugar derivatives either in isolation or from glycopeptides or glycoproteins. The methods comprise producing sugar hydrazones, sugar pyrazoles, glycosylpyrazones, azoglycan dyes and hydrazoglycan dyes. The present invention also relates to the removal of O-glycans from glycopeptides or glycoproteins, immobilising reducing sugars onto solid supports and methods to obtain sugars from a glycopeptide or glycoprotein comprising subjecting the glycopeptide or glycoprotein to solid-phase Edman degradation followed by separating and characterising the sugars.

Original language	English
Patent number	AU1995012681
IPC	C07H 1/00,C07H 5/04,C07H 13/04,C07H 15/26,C07H 19/04,C07K 1/107,C07K 1/12,C08B 37/02,C08J 7/12,C09B 29/46,C09B 29/50,C09B 39/00,C09B 55/00,G01N 33/00,G01N 33/68
Priority date	9/12/93
Publication status	Published - 8 Jul 1999

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https://patentscope.wipo.int/search/en/detail.jsf?docId=AU180645145

Glycosylhydrazines, preparation, immobilization and reactions of: glycoprotein analysis and O-glycan removal
Redmond, J. W. (Inventor), Packer, N. H. (Inventor), Gooley, A. A. (Inventor), Williams, K. L. (Inventor), Batley, M. (Inventor), Kerr, W. C. (Inventor), Pisano, A. (Inventor), Tweeddale, H. J. (Inventor) & Cooper, C. A. (Inventor), 3 Nov 1998, IPC No. C07H 5/06, C07H 1/00, C07H 1/08, C07H 9/00, C07H 9/06, C07H 11/00, C07K 1/00, C07K 1/12, C09B 29/00, C09B 29/50, Patent No. US5831077, Priority date 9 Dec 1993, Priority No. AUPM289093
Research output: Patent

Open Access
Glycozylhydrazines, preparation, immobilization and reactions of: glycoprotein analysis and O-glycan removal
Redmond, J. W. (Inventor), Packer, N. H. (Inventor), Gooley, A. A. (Inventor), Williams, K. L. (Inventor), Batley, M. (Inventor), Kett, W. C. (Inventor), Pisano, A. (Inventor), Tweeddale, H. J. (Inventor) & Cooper, C. A. (Inventor), 15 Jun 1995, (Submitted) IPC No. C07H 1/08 2006.1, C07H 9/06 2006.1, C07H 11/00 2006.1, C07K 1/12 2006.1, C09B 29/50 2006.1, Patent No. WO1995015969, Priority date 9 Dec 1993, Priority No. AUPM2890
Research output: Patent

Cite this

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title = "Glycozylhydrazines, preparation, immobilization and reactions of: glycoprotein analysis and O-glycan removal",

abstract = "The present invention consists in methods of preparing sugar derivatives either in isolation or from glycopeptides or glycoproteins. The methods comprise producing sugar hydrazones, sugar pyrazoles, glycosylpyrazones, azoglycan dyes and hydrazoglycan dyes. The present invention also relates to the removal of O-glycans from glycopeptides or glycoproteins, immobilising reducing sugars onto solid supports and methods to obtain sugars from a glycopeptide or glycoprotein comprising subjecting the glycopeptide or glycoprotein to solid-phase Edman degradation followed by separating and characterising the sugars.",

author = "Michael Batley and Cooper, \{Catherine Anne\} and Gooley, \{Andrew Arthur\} and Kett, \{Warren Charles\} and Packer, \{Nicolle Hannah\} and Anthony Pisano and Redmond, \{John William\} and Tweeddale, \{Helen Joan\} and Williams, \{Keith Leslie\}",

year = "1999",

month = jul,

day = "8",

language = "English",

type = "Patent",

note = "AU1995012681; C07H 1/00,C07H 5/04,C07H 13/04,C07H 15/26,C07H 19/04,C07K 1/107,C07K 1/12,C08B 37/02,C08J 7/12,C09B 29/46,C09B 29/50,C09B 39/00,C09B 55/00,G01N 33/00,G01N 33/68",

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TY - PAT

T1 - Glycozylhydrazines, preparation, immobilization and reactions of: glycoprotein analysis and O-glycan removal

AU - Batley, Michael

AU - Cooper, Catherine Anne

AU - Gooley, Andrew Arthur

AU - Kett, Warren Charles

AU - Packer, Nicolle Hannah

AU - Pisano, Anthony

AU - Redmond, John William

AU - Tweeddale, Helen Joan

AU - Williams, Keith Leslie

PY - 1999/7/8

Y1 - 1999/7/8

N2 - The present invention consists in methods of preparing sugar derivatives either in isolation or from glycopeptides or glycoproteins. The methods comprise producing sugar hydrazones, sugar pyrazoles, glycosylpyrazones, azoglycan dyes and hydrazoglycan dyes. The present invention also relates to the removal of O-glycans from glycopeptides or glycoproteins, immobilising reducing sugars onto solid supports and methods to obtain sugars from a glycopeptide or glycoprotein comprising subjecting the glycopeptide or glycoprotein to solid-phase Edman degradation followed by separating and characterising the sugars.

AB - The present invention consists in methods of preparing sugar derivatives either in isolation or from glycopeptides or glycoproteins. The methods comprise producing sugar hydrazones, sugar pyrazoles, glycosylpyrazones, azoglycan dyes and hydrazoglycan dyes. The present invention also relates to the removal of O-glycans from glycopeptides or glycoproteins, immobilising reducing sugars onto solid supports and methods to obtain sugars from a glycopeptide or glycoprotein comprising subjecting the glycopeptide or glycoprotein to solid-phase Edman degradation followed by separating and characterising the sugars.

M3 - Patent

M1 - AU1995012681

ER -

Glycozylhydrazines, preparation, immobilization and reactions of: glycoprotein analysis and O-glycan removal

Abstract

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Research output

Glycosylhydrazines, preparation, immobilization and reactions of: glycoprotein analysis and O-glycan removal

Glycozylhydrazines, preparation, immobilization and reactions of: glycoprotein analysis and O-glycan removal

Cite this