Abstract
In the grinding of paracetamol, lactose and sucrose in a vibratory ball mill, it is found that an equilibrium is rapidly attained due to the agglomeration of ground particles. The existence of this agglomerative phase of comminution has been extensively reported in the literature. This study investigates prolonged vibratory ball milling as a means of pharmaceutical granulation. The granules are produced from the agglomeration of very fine particles and become more compacted as comminution proceeds.
Original language | English |
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Pages (from-to) | 91-95 |
Number of pages | 5 |
Journal | Powder Technology |
Volume | 28 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1981 |
Externally published | Yes |