TY - JOUR
T1 - Guidelines on guidelines
T2 - Focus on isolated systolic hypertension in youth
AU - O'Rourke, Michael F.
AU - Adji, Audrey
PY - 2013/4
Y1 - 2013/4
N2 - Current guidelines on isolated systolic hypertension (ISH) suggest the same treatment to patients of all ages. Application of these guidelines in youth with ISH may not be appropriate, as presently no data show adverse outcome or benefit of drug therapy in this group. Simple noninvasive tonometric techniques now enable physicians to measure the central aortic pressure waveform and amplification of the pressure pulse. ISH in youth is usually caused by high amplification of the central pressure wave, whereas ISH in the elderly (>age 60) is attributable to aortic stiffening. This is the only group with ISH shown to have an adverse prognosis and to warrant drug therapy.
AB - Current guidelines on isolated systolic hypertension (ISH) suggest the same treatment to patients of all ages. Application of these guidelines in youth with ISH may not be appropriate, as presently no data show adverse outcome or benefit of drug therapy in this group. Simple noninvasive tonometric techniques now enable physicians to measure the central aortic pressure waveform and amplification of the pressure pulse. ISH in youth is usually caused by high amplification of the central pressure wave, whereas ISH in the elderly (>age 60) is attributable to aortic stiffening. This is the only group with ISH shown to have an adverse prognosis and to warrant drug therapy.
UR - http://www.scopus.com/inward/record.url?scp=84875218692&partnerID=8YFLogxK
U2 - 10.1097/HJH.0b013e32835d8230
DO - 10.1097/HJH.0b013e32835d8230
M3 - Review article
C2 - 23412425
AN - SCOPUS:84875218692
SN - 0263-6352
VL - 31
SP - 649
EP - 654
JO - Journal of Hypertension
JF - Journal of Hypertension
IS - 4
ER -