TY - JOUR
T1 - Health-related quality of life in maxillectomy patients undergoing dentoalveolar rehabilitation
AU - Petrides, George A.
AU - Dunn, Masako
AU - Charters, Emma
AU - Venchiarutti, Rebecca
AU - Cheng, Kai
AU - Froggatt, Catriona
AU - Mukherjee, Payal
AU - Wallace, Christine
AU - Howes, Dale
AU - Leinkram, David
AU - Singh, Jasvir
AU - Nguyen, Kevin
AU - Low, Tsu-Hui Hubert
AU - Ch'ng, Sydney
AU - Wykes, James
AU - Clark, Jonathan R.
PY - 2022/3
Y1 - 2022/3
N2 - Objectives: Surgical resection of the maxilla impairs aesthetics, speech, swallowing, and mastication. Maxillary reconstruction is increasingly performed with virtual surgical planning (VSP) to enhance functional dental rehabilitation with a conventional denture or osseointegrated implants. The aim of this study was to determine whether dental status and VSP is associated with health-related quality of life (HRQOL) and function in patients who have undergone maxillectomy. Materials and methods: A cross-sectional study was conducted among patients who underwent free flap reconstruction or obturation of the maxilla between July 2009 and December 2020. The FACE-Q Head and Neck Cancer (FACE-Q) module, M.D. Anderson Dysphagia Inventory (MDADI), and Speech Handicap Index (SHI) were used to evaluate HRQOL. Results: Forty-three patients (response rate 59%) completed questionnaires and 48% underwent dental rehabilitation. In Okay Class II and III defects, adjusting for the effect of radiotherapy and time from surgery, there was a positive association between denture status and FACE-Q smiling (p = 0.020), eating (p = 0.012), smiling (p = 0.015), and MDADI global (p = 0.015), emotional (p = 0.027), functional (p = 0.028), and composite (p = 0.029) scores. VSP was associated with FACE-Q swallowing (p = 0.005), drooling (p = 0.030), eating (p = 0.008), smiling (p = 0.021), MDADI global (p = 0.017), emotional (p = 0.041), functional (p = 0.040), composite (p = 0.038), and SHI total scores (p = 0.042). Conclusions: Dentoalveolar rehabilitation and VSP were associated with higher HRQOL scores relating to eating and drinking, smiling, and speaking.
AB - Objectives: Surgical resection of the maxilla impairs aesthetics, speech, swallowing, and mastication. Maxillary reconstruction is increasingly performed with virtual surgical planning (VSP) to enhance functional dental rehabilitation with a conventional denture or osseointegrated implants. The aim of this study was to determine whether dental status and VSP is associated with health-related quality of life (HRQOL) and function in patients who have undergone maxillectomy. Materials and methods: A cross-sectional study was conducted among patients who underwent free flap reconstruction or obturation of the maxilla between July 2009 and December 2020. The FACE-Q Head and Neck Cancer (FACE-Q) module, M.D. Anderson Dysphagia Inventory (MDADI), and Speech Handicap Index (SHI) were used to evaluate HRQOL. Results: Forty-three patients (response rate 59%) completed questionnaires and 48% underwent dental rehabilitation. In Okay Class II and III defects, adjusting for the effect of radiotherapy and time from surgery, there was a positive association between denture status and FACE-Q smiling (p = 0.020), eating (p = 0.012), smiling (p = 0.015), and MDADI global (p = 0.015), emotional (p = 0.027), functional (p = 0.028), and composite (p = 0.029) scores. VSP was associated with FACE-Q swallowing (p = 0.005), drooling (p = 0.030), eating (p = 0.008), smiling (p = 0.021), MDADI global (p = 0.017), emotional (p = 0.041), functional (p = 0.040), composite (p = 0.038), and SHI total scores (p = 0.042). Conclusions: Dentoalveolar rehabilitation and VSP were associated with higher HRQOL scores relating to eating and drinking, smiling, and speaking.
KW - Dental implants
KW - Head and Neck cancer
KW - Maxilla
KW - Mouth rehabilitation
KW - Oral cancer
KW - Quality of life
KW - Surgical reconstruction
UR - http://www.scopus.com/inward/record.url?scp=85123826078&partnerID=8YFLogxK
U2 - 10.1016/j.oraloncology.2022.105757
DO - 10.1016/j.oraloncology.2022.105757
M3 - Article
C2 - 35121398
AN - SCOPUS:85123826078
SN - 1368-8375
VL - 126
SP - 1
EP - 10
JO - Oral Oncology
JF - Oral Oncology
M1 - 105757
ER -