Heart failure and thermoregulatory control: can patients with heart failure handle the heat?

Bryce N. Balmain*, Surendran Sabapathy, Ollie Jay, Julie Adsett, Glenn M. Stewart, Rohan Jayasinghe, Norman R. Morris

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)


Upon heat exposure, the thermoregulatory system evokes reflex increases in sweating and skin blood flow responses to facilitate heat dissipation and maintain heat balance to prevent the continuing rise in core temperature. These heat dissipating responses are mediated primarily by autonomic and cardiovascular adjustments; which, if attenuated, may compromise thermoregulatory control. In patients with heart failure (HF), the neurohumoral and cardiovascular dysfunction that underpins this condition may potentially impair thermoregulatory responses and, consequently, place these patients at a greater risk of heat-related illness. The aim of this review is to describe thermoregulatory mechanisms and the factors that may increase the risk of heat-related illness in patients with HF. An understanding of the mechanisms responsible for impaired thermoregulatory control in HF patients is of particular importance, given the current and projected increase in frequency and intensity of heat waves, as well as the promotion of regular exercise as a therapeutic modality. Furthermore, novel therapeutic strategies that may improve thermoregulatory control in HF, and the clinical relevance of this work in this population will be discussed.

Original languageEnglish
Pages (from-to)621-627
Number of pages7
JournalJournal of Cardiac Failure
Issue number8
Publication statusPublished - Aug 2017
Externally publishedYes


  • Cardiovascular
  • Heat
  • Thermoregulation


Dive into the research topics of 'Heart failure and thermoregulatory control: can patients with heart failure handle the heat?'. Together they form a unique fingerprint.

Cite this