Hemodynamic influence of different pulmonary stenosis degree in glenn procedure: a numerical study

Liancai Ma, Youjun Liu*, Xi Zhao, Xiaochen Ren, Fan Bai, Jinli Ding, Mingzi Zhang, Wenxin Wang, Jinsheng Xie, Hao Zhang, Zhou Zhao, Hua Han

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)
32 Downloads (Pure)


Background. Single ventricle disease is treated by Glenn surgery. It is generally accompanied by stenosis on a pulmonary artery or its branches, which has great effect on hemodynamics. This study investigated the hemodynamic influence of different pulmonary stenosis degree in Glenn procedure. Materials. Four three-dimensional Glenn models with different left pulmonary artery stenosis rates as, respectively, 0% (model 1), 25% (model 2), 50% (model 3), and 75% (model 4) by the diameter were generated. Method. Geometric multiscale analysis method was used in the numerical simulations by coupling the lumped parameter model (LPM) and three-dimensional model. Results. During one cardiac cycle, the flow ratio between left pulmonary artery and superior vena cava was about 0.49 for models 1, 2, and 3, while the ratio decreased to 0.34 for model 4. On the other hand, hemodynamics parameters like power loss and oscillation shear index show complications of the stenosis to the postoperative development. Conclusion. When the stenosis rate is above 75%, it is suggested to treat stenosis before Glenn procedure, while when the stenosis rate is below 50%, there is no necessity to pay attention to it due to the little effect it makes.

Original languageEnglish
Article number472370
Pages (from-to)1-10
Number of pages10
JournalAdvances in Mechanical Engineering
Publication statusPublished - 2014
Externally publishedYes

Bibliographical note

Copyright the Author(s) 2015. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.


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