TY - JOUR
T1 - Hemodynamic influence of different pulmonary stenosis degree in glenn procedure
T2 - a numerical study
AU - Ma, Liancai
AU - Liu, Youjun
AU - Zhao, Xi
AU - Ren, Xiaochen
AU - Bai, Fan
AU - Ding, Jinli
AU - Zhang, Mingzi
AU - Wang, Wenxin
AU - Xie, Jinsheng
AU - Zhang, Hao
AU - Zhao, Zhou
AU - Han, Hua
N1 - Copyright the Author(s) 2015. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.
PY - 2014
Y1 - 2014
N2 - Background. Single ventricle disease is treated by Glenn surgery. It is generally accompanied by stenosis on a pulmonary artery or its branches, which has great effect on hemodynamics. This study investigated the hemodynamic influence of different pulmonary stenosis degree in Glenn procedure. Materials. Four three-dimensional Glenn models with different left pulmonary artery stenosis rates as, respectively, 0% (model 1), 25% (model 2), 50% (model 3), and 75% (model 4) by the diameter were generated. Method. Geometric multiscale analysis method was used in the numerical simulations by coupling the lumped parameter model (LPM) and three-dimensional model. Results. During one cardiac cycle, the flow ratio between left pulmonary artery and superior vena cava was about 0.49 for models 1, 2, and 3, while the ratio decreased to 0.34 for model 4. On the other hand, hemodynamics parameters like power loss and oscillation shear index show complications of the stenosis to the postoperative development. Conclusion. When the stenosis rate is above 75%, it is suggested to treat stenosis before Glenn procedure, while when the stenosis rate is below 50%, there is no necessity to pay attention to it due to the little effect it makes.
AB - Background. Single ventricle disease is treated by Glenn surgery. It is generally accompanied by stenosis on a pulmonary artery or its branches, which has great effect on hemodynamics. This study investigated the hemodynamic influence of different pulmonary stenosis degree in Glenn procedure. Materials. Four three-dimensional Glenn models with different left pulmonary artery stenosis rates as, respectively, 0% (model 1), 25% (model 2), 50% (model 3), and 75% (model 4) by the diameter were generated. Method. Geometric multiscale analysis method was used in the numerical simulations by coupling the lumped parameter model (LPM) and three-dimensional model. Results. During one cardiac cycle, the flow ratio between left pulmonary artery and superior vena cava was about 0.49 for models 1, 2, and 3, while the ratio decreased to 0.34 for model 4. On the other hand, hemodynamics parameters like power loss and oscillation shear index show complications of the stenosis to the postoperative development. Conclusion. When the stenosis rate is above 75%, it is suggested to treat stenosis before Glenn procedure, while when the stenosis rate is below 50%, there is no necessity to pay attention to it due to the little effect it makes.
UR - http://www.scopus.com/inward/record.url?scp=84935015769&partnerID=8YFLogxK
U2 - 10.1155/2014/472370
DO - 10.1155/2014/472370
M3 - Article
AN - SCOPUS:84935015769
SN - 1687-8132
VL - 2014
SP - 1
EP - 10
JO - Advances in Mechanical Engineering
JF - Advances in Mechanical Engineering
M1 - 472370
ER -