The 2,6-diazabicyclic carbinolamine 17 has been isolated from the reaction of the 1,2-diazabicyclic ketone 1 in methanol plus Et 3N; 17 gives the same products (13 and 14) on further reaction in methanol as does 1. The reaction of ketone 1b with base gives the enamino ketone 30 plus glycine, indicating attack at the carbonyl group. Four reaction pathways of 1 are summarized.
|Number of pages||5|
|Journal||Journal of Organic Chemistry|
|Publication status||Published - 1978|