High-resolution deep-tissue optical imaging using anti-Stokes phosphors

A. P. Popov; A. V. Karmenyan; A. V. Bykov; E. V. Khaydukov; A. V. Nechaev; O. A. Bibikova; V. Ya Panchenko; V. A. Semchishen; V. N. Seminogov; A. S. Akhmanov; V. I. Sokolov; M. T. Kinnunen; V. V. Tuchin; A. V. Zvyagin

doi:10.1117/12.2032805

High-resolution deep-tissue optical imaging using anti-Stokes phosphors

A. P. Popov, A. V. Karmenyan, A. V. Bykov, E. V. Khaydukov, A. V. Nechaev, O. A. Bibikova, V. Ya Panchenko, V. A. Semchishen, V. N. Seminogov, A. S. Akhmanov, V. I. Sokolov, M. T. Kinnunen, V. V. Tuchin, A. V. Zvyagin

Research output: Chapter in Book/Report/Conference proceeding › Conference proceeding contribution › peer-review

5 Citations (Scopus)

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Abstract

We report on the high-resolution deep-tissue imaging using novel water-dispersible upconversion nanoparticles (UCNPs) β-NaYF4:Yb ^3+:Tm³⁺. Luminescence from the UCNP embedded into tissue-mimicking phantoms at the depth of 4 mm epi-illuminated with 975-nm laser radiation was detected. Fiber-optic detection shows 2-times better resolution compared with that obtained using CCD-based imaging modality. The conversion efficiency of upconversion particles and their cytotoxicity to HeLa cells were also investigated and reported.

Original language	English
Title of host publication	Novel Biophotonic Techniques and Applications II
Subtitle of host publication	Proceedings of SPIE
Editors	Alex Vitkin, Arjen Amelink
Place of Publication	Bellingham, WA
Publisher	SPIE
Pages	1-8
Number of pages	8
Volume	8801
ISBN (Print)	9780819496508
DOIs	https://doi.org/10.1117/12.2032805
Publication status	Published - 2013
Event	European Conference on Biomedical Optics, ECBO 2013 - Munich, Germany Duration: 12 May 2013 → 16 May 2013

Other

Other	European Conference on Biomedical Optics, ECBO 2013
Country/Territory	Germany
City	Munich
Period	12/05/13 → 16/05/13

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Popov, A. P., Karmenyan, A. V., Bykov, A. V., Khaydukov, E. V., Nechaev, A. V., Bibikova, O. A., Panchenko, V. Y., Semchishen, V. A., Seminogov, V. N., Akhmanov, A. S., Sokolov, V. I., Kinnunen, M. T., Tuchin, V. V., & Zvyagin, A. V. (2013). High-resolution deep-tissue optical imaging using anti-Stokes phosphors. In A. Vitkin, & A. Amelink (Eds.), Novel Biophotonic Techniques and Applications II: Proceedings of SPIE (Vol. 8801, pp. 1-8). Article 88010C SPIE. https://doi.org/10.1117/12.2032805

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title = "High-resolution deep-tissue optical imaging using anti-Stokes phosphors",

abstract = "We report on the high-resolution deep-tissue imaging using novel water-dispersible upconversion nanoparticles (UCNPs) β-NaYF4:Yb 3+:Tm3+. Luminescence from the UCNP embedded into tissue-mimicking phantoms at the depth of 4 mm epi-illuminated with 975-nm laser radiation was detected. Fiber-optic detection shows 2-times better resolution compared with that obtained using CCD-based imaging modality. The conversion efficiency of upconversion particles and their cytotoxicity to HeLa cells were also investigated and reported.",

author = "Popov, \{A. P.\} and Karmenyan, \{A. V.\} and Bykov, \{A. V.\} and Khaydukov, \{E. V.\} and Nechaev, \{A. V.\} and Bibikova, \{O. A.\} and Panchenko, \{V. Ya\} and Semchishen, \{V. A.\} and Seminogov, \{V. N.\} and Akhmanov, \{A. S.\} and Sokolov, \{V. I.\} and Kinnunen, \{M. T.\} and Tuchin, \{V. V.\} and Zvyagin, \{A. V.\}",

year = "2013",

doi = "10.1117/12.2032805",

language = "English",

isbn = "9780819496508",

volume = "8801",

pages = "1--8",

editor = "Alex Vitkin and Arjen Amelink",

booktitle = "Novel Biophotonic Techniques and Applications II",

publisher = "SPIE",

address = "United States",

note = "European Conference on Biomedical Optics, ECBO 2013 ; Conference date: 12-05-2013 Through 16-05-2013",

}

Popov, AP, Karmenyan, AV, Bykov, AV, Khaydukov, EV, Nechaev, AV, Bibikova, OA, Panchenko, VY, Semchishen, VA, Seminogov, VN, Akhmanov, AS, Sokolov, VI, Kinnunen, MT, Tuchin, VV & Zvyagin, AV 2013, High-resolution deep-tissue optical imaging using anti-Stokes phosphors. in A Vitkin & A Amelink (eds), Novel Biophotonic Techniques and Applications II: Proceedings of SPIE. vol. 8801, 88010C, SPIE, Bellingham, WA, pp. 1-8, European Conference on Biomedical Optics, ECBO 2013, Munich, Germany, 12/05/13. https://doi.org/10.1117/12.2032805

High-resolution deep-tissue optical imaging using anti-Stokes phosphors. / Popov, A. P.; Karmenyan, A. V.; Bykov, A. V. et al.
Novel Biophotonic Techniques and Applications II: Proceedings of SPIE. ed. / Alex Vitkin; Arjen Amelink. Vol. 8801 Bellingham, WA: SPIE, 2013. p. 1-8 88010C.

Research output: Chapter in Book/Report/Conference proceeding › Conference proceeding contribution › peer-review

TY - GEN

T1 - High-resolution deep-tissue optical imaging using anti-Stokes phosphors

AU - Popov, A. P.

AU - Karmenyan, A. V.

AU - Bykov, A. V.

AU - Khaydukov, E. V.

AU - Nechaev, A. V.

AU - Bibikova, O. A.

AU - Panchenko, V. Ya

AU - Semchishen, V. A.

AU - Seminogov, V. N.

AU - Akhmanov, A. S.

AU - Sokolov, V. I.

AU - Kinnunen, M. T.

AU - Tuchin, V. V.

AU - Zvyagin, A. V.

PY - 2013

Y1 - 2013

N2 - We report on the high-resolution deep-tissue imaging using novel water-dispersible upconversion nanoparticles (UCNPs) β-NaYF4:Yb 3+:Tm3+. Luminescence from the UCNP embedded into tissue-mimicking phantoms at the depth of 4 mm epi-illuminated with 975-nm laser radiation was detected. Fiber-optic detection shows 2-times better resolution compared with that obtained using CCD-based imaging modality. The conversion efficiency of upconversion particles and their cytotoxicity to HeLa cells were also investigated and reported.

AB - We report on the high-resolution deep-tissue imaging using novel water-dispersible upconversion nanoparticles (UCNPs) β-NaYF4:Yb 3+:Tm3+. Luminescence from the UCNP embedded into tissue-mimicking phantoms at the depth of 4 mm epi-illuminated with 975-nm laser radiation was detected. Fiber-optic detection shows 2-times better resolution compared with that obtained using CCD-based imaging modality. The conversion efficiency of upconversion particles and their cytotoxicity to HeLa cells were also investigated and reported.

UR - https://www.scopus.com/pages/publications/84883891236

U2 - 10.1117/12.2032805

DO - 10.1117/12.2032805

M3 - Conference proceeding contribution

AN - SCOPUS:84883891236

SN - 9780819496508

VL - 8801

SP - 1

EP - 8

BT - Novel Biophotonic Techniques and Applications II

A2 - Vitkin, Alex

A2 - Amelink, Arjen

PB - SPIE

CY - Bellingham, WA

T2 - European Conference on Biomedical Optics, ECBO 2013

Y2 - 12 May 2013 through 16 May 2013

ER -

High-resolution deep-tissue optical imaging using anti-Stokes phosphors

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