Highly enantioselective recombinant thermoalkalophilic lipases from Geobacillus and Bacillus sp

Lauren M Hutchins, L Hunter, N Ehya, MD Gibbs, Peter Bergquist, Craig A. Hutton

    Research output: Contribution to journalArticlepeer-review

    7 Citations (Scopus)


    Thermoalkalophilic lipases from Geobacillus and Bacillus strains have been cloned and characterised, several of which show excellent activity and enantioselectivity towards various substrates. The hydrolysis of methyl 2-methyldecanoate proceeds to give (R)-2-methyldecanoic acid in good yield and >99% enantiomeric excess (E >200). Crown Copyright (C) 2004 Published by Elsevier Ltd. All rights reserved.

    Original languageEnglish
    Pages (from-to)2975-2980
    Number of pages6
    JournalTetrahedron Asymmetry
    Issue number18
    Publication statusPublished - 20 Sep 2004


    • PCR

    Cite this