Hjerneskademarkøren S100B kan mindske brugen af computertomografi ved lette hovedtraumer - sekundærpublikation

Jacob Bertram Springborg; Johan Undén; Tor Ingebrigtsen; Bertil Romner

Hjerneskademarkøren S100B kan mindske brugen af computertomografi ved lette hovedtraumer - sekundærpublikation

Translated title of the contribution: Managing patients with minor head injury with a simple blood test - secondary publication

Jacob Bertram Springborg^*, Johan Undén, Tor Ingebrigtsen, Bertil Romner

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

The risk of acute intracranial complications after minor head injury (MHI) is low. Despite this, computed tomography (CT) is generally recommended with clinical observation as a secondary option. Both options have disadvantages. Clinical studies have shown the potential advantages of using the biomarker S100B. The specificity of S100B is low, but a high sensitivity for brain damage results in a clinically useful, high negative predictive value (NPV). Integration of S100B into existing management routines can reduce the need for CT scans or admission by over 30%.

Translated title of the contribution	Managing patients with minor head injury with a simple blood test - secondary publication
Original language	Danish
Pages (from-to)	978-981
Number of pages	4
Journal	Ugeskrift for Laeger
Volume	171
Issue number	12
Publication status	Published - Mar 2009
Externally published	Yes

Cite this

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abstract = "The risk of acute intracranial complications after minor head injury (MHI) is low. Despite this, computed tomography (CT) is generally recommended with clinical observation as a secondary option. Both options have disadvantages. Clinical studies have shown the potential advantages of using the biomarker S100B. The specificity of S100B is low, but a high sensitivity for brain damage results in a clinically useful, high negative predictive value (NPV). Integration of S100B into existing management routines can reduce the need for CT scans or admission by over 30%.",

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AU - Undén, Johan

AU - Ingebrigtsen, Tor

AU - Romner, Bertil

PY - 2009/3

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N2 - The risk of acute intracranial complications after minor head injury (MHI) is low. Despite this, computed tomography (CT) is generally recommended with clinical observation as a secondary option. Both options have disadvantages. Clinical studies have shown the potential advantages of using the biomarker S100B. The specificity of S100B is low, but a high sensitivity for brain damage results in a clinically useful, high negative predictive value (NPV). Integration of S100B into existing management routines can reduce the need for CT scans or admission by over 30%.

AB - The risk of acute intracranial complications after minor head injury (MHI) is low. Despite this, computed tomography (CT) is generally recommended with clinical observation as a secondary option. Both options have disadvantages. Clinical studies have shown the potential advantages of using the biomarker S100B. The specificity of S100B is low, but a high sensitivity for brain damage results in a clinically useful, high negative predictive value (NPV). Integration of S100B into existing management routines can reduce the need for CT scans or admission by over 30%.

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IS - 12

ER -

Hjerneskademarkøren S100B kan mindske brugen af computertomografi ved lette hovedtraumer - sekundærpublikation

Abstract

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