Holographic digital fourier microscopy for selective imaging of biological tissue

Sergey A. Alexandrov, P. Meredith, T. J. McIntyre, A. V. Zvyagin*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


We present an application of digital Fourier holography for selective imaging of scatterers with different sizes in turbid media such as biological tissues. A combination of Fourier holography and high-resolution digital recording, digital Fourier microscopy (DFM) permits crucial flexibility in applying filtering to highlight scatterers of interest In the tissue. The high-resolution digital hologram is a result of the collation of Fourier holographic frames to form a large-size composite hologram. It is expected that DFM has an improved signal-to-noise ratio as compared to conventional direct digital imaging, e.g., phase microscopy, as applied to imaging of small-size objects. The demonstration of the Fourier filtering capacity of DFM using a biological phantom represents the main focus of this article.

Original languageEnglish
Pages (from-to)253-258
Number of pages6
JournalInternational Journal of Imaging Systems and Technology
Issue number6
Publication statusPublished - 2004
Externally publishedYes


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