TY - JOUR
T1 - Homocysteine and retinal vein occlusion
T2 - A Population-based study
AU - Chua, Brian
AU - Kifley, Annette
AU - Wong, Tien Y.
AU - Mitchell, Paul
PY - 2005/1
Y1 - 2005/1
N2 - To report population data on the association between homocysteinemia and retinal vein occlusion (RVO). Cross-sectional, population-based study. Total serum homocysteine (tHcy) was estimated in subjects attending the second Blue Mountains Eye Study (BMES) (n = 3509, aged >49 years). Its association with RVO (graded from retinal photographs) was examined. Homocysteine was more strongly associated with RVO in younger than older participants. In those aged <70 years, homocysteine levels >15 μmol/l were associated with increased odds of RVO, odds ratio (OR) 3.76; 95% confidence interval (CI) 1.06-13.40, in multivariable-adjusted analyses. Each 1 μmol/l increase in homocysteine was associated with a 7% increased odds of RVO, OR 1.07; CI 0.99-1.17 (P =. 08). This population-based study showed that elevated serum homocysteine is associated with the presence of RVO, independent of other risk factors.
AB - To report population data on the association between homocysteinemia and retinal vein occlusion (RVO). Cross-sectional, population-based study. Total serum homocysteine (tHcy) was estimated in subjects attending the second Blue Mountains Eye Study (BMES) (n = 3509, aged >49 years). Its association with RVO (graded from retinal photographs) was examined. Homocysteine was more strongly associated with RVO in younger than older participants. In those aged <70 years, homocysteine levels >15 μmol/l were associated with increased odds of RVO, odds ratio (OR) 3.76; 95% confidence interval (CI) 1.06-13.40, in multivariable-adjusted analyses. Each 1 μmol/l increase in homocysteine was associated with a 7% increased odds of RVO, OR 1.07; CI 0.99-1.17 (P =. 08). This population-based study showed that elevated serum homocysteine is associated with the presence of RVO, independent of other risk factors.
UR - http://www.scopus.com/inward/record.url?scp=11844254506&partnerID=8YFLogxK
U2 - 10.1016/j.ajo.2004.06.084
DO - 10.1016/j.ajo.2004.06.084
M3 - Article
C2 - 15652845
AN - SCOPUS:11844254506
VL - 139
SP - 181
EP - 182
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
SN - 0002-9394
IS - 1
ER -