Hospital variability of postoperative sepsis and sepsis-related mortality after elective coronary artery bypass grafting surgery

Lixin Ou, Jack Chen, Arthas Flabouris, Ken Hillman, Michael Parr, Rinaldo Bellomo

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Purpose: Hospital variability of postoperative sepsis and sepsis-related mortality after elective CABG surgery was not known in Australia. Material and methods: Population-based analysis of all elective patients who underwent CABG surgery in public and private hospitals between 2007 and 2014 using linked data from the state-wide Admitted Patient Data Collection and the NSW Registry of Births, Deaths, and Marriages. Results: We identified 18,928 (9464 pairs) matched patients who had elective CABG surgery in public hospitals (n = 9) and private hospitals (n = 13) during the study period. When compared to public hospital patients, private hospital patients had a significantly lower rate of post-CABG sepsis (13.3 vs 20.4 per 1000 admissions, P < 0.001; treatment effects: −7.1, 95%CI: −11.1 to −3.3), a lower in-hospital mortality rate (6.1 vs 9.9 per 1000 admissions, P = 0.006; treatment effects: −3.8, 95%CI: −6.5 to −1.1), and a lower rate of 30-day readmission (11.9% vs 13.9%, P < 0.001; treatment effects: −2.0%, 95%CI: −3.1% to −1.0%). In addition, for both public and private hospital groups, there were significant differences for all outcomes when comparing the worst and best performance quintile hospitals. Conclusions: Hospital variability of postoperative sepsis, in-hospital mortality and readmission after elective CABG existed between and within public and private hospitals.

LanguageEnglish
Pages232-237
Number of pages6
JournalJournal of Critical Care
Volume47
DOIs
Publication statusPublished - 1 Oct 2018

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Private Hospitals
Public Hospitals
Coronary Artery Bypass
Sepsis
Mortality
Hospital Mortality
Patient Readmission
Marriage
Registries
Therapeutics
Parturition
Population

Keywords

  • Coronary artery bypass grafting
  • Hospital mortality
  • Postoperative sepsis
  • Readmission

Cite this

Ou, Lixin ; Chen, Jack ; Flabouris, Arthas ; Hillman, Ken ; Parr, Michael ; Bellomo, Rinaldo. / Hospital variability of postoperative sepsis and sepsis-related mortality after elective coronary artery bypass grafting surgery. In: Journal of Critical Care. 2018 ; Vol. 47. pp. 232-237.
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abstract = "Purpose: Hospital variability of postoperative sepsis and sepsis-related mortality after elective CABG surgery was not known in Australia. Material and methods: Population-based analysis of all elective patients who underwent CABG surgery in public and private hospitals between 2007 and 2014 using linked data from the state-wide Admitted Patient Data Collection and the NSW Registry of Births, Deaths, and Marriages. Results: We identified 18,928 (9464 pairs) matched patients who had elective CABG surgery in public hospitals (n = 9) and private hospitals (n = 13) during the study period. When compared to public hospital patients, private hospital patients had a significantly lower rate of post-CABG sepsis (13.3 vs 20.4 per 1000 admissions, P < 0.001; treatment effects: −7.1, 95{\%}CI: −11.1 to −3.3), a lower in-hospital mortality rate (6.1 vs 9.9 per 1000 admissions, P = 0.006; treatment effects: −3.8, 95{\%}CI: −6.5 to −1.1), and a lower rate of 30-day readmission (11.9{\%} vs 13.9{\%}, P < 0.001; treatment effects: −2.0{\%}, 95{\%}CI: −3.1{\%} to −1.0{\%}). In addition, for both public and private hospital groups, there were significant differences for all outcomes when comparing the worst and best performance quintile hospitals. Conclusions: Hospital variability of postoperative sepsis, in-hospital mortality and readmission after elective CABG existed between and within public and private hospitals.",
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Hospital variability of postoperative sepsis and sepsis-related mortality after elective coronary artery bypass grafting surgery. / Ou, Lixin; Chen, Jack; Flabouris, Arthas; Hillman, Ken; Parr, Michael; Bellomo, Rinaldo.

In: Journal of Critical Care, Vol. 47, 01.10.2018, p. 232-237.

Research output: Contribution to journalArticleResearchpeer-review

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