How to assess, control, and manage uncontrolled CRS/nasal polyp patients

Rahuram Sivasubramaniam, Richard J. Harvey*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

2 Citations (Scopus)

Abstract

Purpose of Review: Chronic rhinosinusitis (CRS) is a multidimensional inflammatory disorder of the nose and paranasal sinuses. We reviewed the recent literature to identify improved methods to assess, control, and manage these difficult to control patients. Recent Findings: The role of endotyping in CRS has offered a better understanding of the underlying pathophysiology and allows for more targeted treatment. The understanding of systemic disorders and their role in CRS and the importance of topical treatment reaching the sinuses has also allowed for better control of these patients. Summary: We have provided some of the commonly identified causes for uncontrolled CRS and a sensible approach to assessing these patients. We have also focused on common areas of pitfalls in the surgery and choice of patients and the role for ongoing systemic treatment. The future of managing this difficult condition includes endotyping using inflammatory markers and individualizing the treatment to the patient by using specific monoclonal antibodies.

Original languageEnglish
Article number58
Pages (from-to)1-10
Number of pages10
JournalCurrent Allergy and Asthma Reports
Volume17
Issue number9
DOIs
Publication statusPublished - 1 Sep 2017

Keywords

  • chronic rhinosinusitis
  • nasal polyposis
  • recalcitrant sinusitis
  • revision sinus surgery
  • uncontrolled sinusitis

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