Identifying long-term patterns and predictors of concurrent psychotropic medicine use in residential aged care using group-based multi-trajectory modelling: the ‘MEDTRAC-Psychotropics’ longitudinal cohort study

Nasir Wabe; Isabelle Meulenbroeks; Desiree Chantelle Firempong; Rachel Urwin; Andrea Timothy; Magdalena Z. Raban; Virginia Mumford; Johanna Westbrook

doi:10.1007/s41999-025-01171-6

Identifying long-term patterns and predictors of concurrent psychotropic medicine use in residential aged care using group-based multi-trajectory modelling: the ‘MEDTRAC-Psychotropics’ longitudinal cohort study

Nasir Wabe, Isabelle Meulenbroeks, Desiree Chantelle Firempong, Rachel Urwin, Andrea Timothy, Magdalena Z. Raban, Virginia Mumford, Johanna Westbrook

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

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Abstract

Aim: Our study aimed to identify trajectories of concurrent use of three psychotropic medication classes over time and identify predictors of trajectory group membership for residents with and without dementia. Findings: We conducted a retrospective longitudinal cohort study among residents in 30 RACFs in New South Wales, Australia and found that one in three residents with dementia and one in five residents without dementia concurrently use multiple psychotropics often for extended periods, which may put residents at risk. Message: Considering a concerning high rate of concurrent use of multiple psychotropic medicines in RACFs, it is imperative to assess its appropriateness and consider further research and strategies for improved health outcomes.

Original language	English
Pages (from-to)	781-792
Number of pages	12
Journal	European Geriatric Medicine
Volume	16
Issue number	3
Early online date	25 Feb 2025
DOIs	https://doi.org/10.1007/s41999-025-01171-6
Publication status	Published - Jun 2025

Bibliographical note

Copyright the Author(s) 2025. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Keywords

Aged care
Nursing homes
Medication use
Group-based multi-trajectory modelling
Psychotropics

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10.1007/s41999-025-01171-6Licence: CC BY

Publisher version (open access)Final published version, 1.11 MBLicence: CC BY

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A National Aged Care Medication Roundtable - Translating aged care data into action to improve quality of care through collaboration and co-design
Westbrook, J. (Primary Chief Investigator), Gray, L. (Chief Investigator), Bucknall, T. K. (Chief Investigator), Etherton-Beer, C. (Chief Investigator), Newell, B. (Chief Investigator), Raban, M. (Chief Investigator), Caughey, G. (Chief Investigator), Beattie, E. (Chief Investigator), Makeham, M. (Chief Investigator), Braithwaite, J. (Chief Investigator), Jorgensen, M. (Associate Investigator), Saunders, R. (Associate Investigator), Badgery-Parker, T. (Associate Investigator), Stafford, A. (Associate Investigator), Root, J. (Associate Investigator), Jackson , S. (Associate Investigator), Tambree, K. (Associate Investigator), Cook, E. (Associate Investigator), Mumford, V. (Associate Investigator) & Inacio, M. (Associate Investigator)
1/11/21 → 31/10/26
Project: Research
Optimising eHealth systems to improve medication safety and patient outcomes
Raban, M. (Primary Chief Investigator)
1/01/18 → …
Project: Research

Cite this

Wabe, N., Meulenbroeks, I., Firempong, D. C., Urwin, R., Timothy, A., Raban, M. Z., Mumford, V., & Westbrook, J. (2025). Identifying long-term patterns and predictors of concurrent psychotropic medicine use in residential aged care using group-based multi-trajectory modelling: the ‘MEDTRAC-Psychotropics’ longitudinal cohort study. European Geriatric Medicine, 16(3), 781-792. https://doi.org/10.1007/s41999-025-01171-6

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abstract = "Aim: Our study aimed to identify trajectories of concurrent use of three psychotropic medication classes over time and identify predictors of trajectory group membership for residents with and without dementia. Findings: We conducted a retrospective longitudinal cohort study among residents in 30 RACFs in New South Wales, Australia and found that one in three residents with dementia and one in five residents without dementia concurrently use multiple psychotropics often for extended periods, which may put residents at risk. Message: Considering a concerning high rate of concurrent use of multiple psychotropic medicines in RACFs, it is imperative to assess its appropriateness and consider further research and strategies for improved health outcomes.",

keywords = "Aged care, Nursing homes, Medication use, Group-based multi-trajectory modelling, Psychotropics",

author = "Nasir Wabe and Isabelle Meulenbroeks and Firempong, \{Desiree Chantelle\} and Rachel Urwin and Andrea Timothy and Raban, \{Magdalena Z.\} and Virginia Mumford and Johanna Westbrook",

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year = "2025",

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doi = "10.1007/s41999-025-01171-6",

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Wabe, N , Meulenbroeks, I, Firempong, DC, Urwin, R, Timothy, A, Raban, MZ , Mumford, V & Westbrook, J 2025, 'Identifying long-term patterns and predictors of concurrent psychotropic medicine use in residential aged care using group-based multi-trajectory modelling: the ‘MEDTRAC-Psychotropics’ longitudinal cohort study', European Geriatric Medicine, vol. 16, no. 3, pp. 781-792. https://doi.org/10.1007/s41999-025-01171-6

Identifying long-term patterns and predictors of concurrent psychotropic medicine use in residential aged care using group-based multi-trajectory modelling: the ‘MEDTRAC-Psychotropics’ longitudinal cohort study. / Wabe, Nasir ; Meulenbroeks, Isabelle; Firempong, Desiree Chantelle et al.
In: European Geriatric Medicine, Vol. 16, No. 3, 06.2025, p. 781-792.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Identifying long-term patterns and predictors of concurrent psychotropic medicine use in residential aged care using group-based multi-trajectory modelling

T2 - the ‘MEDTRAC-Psychotropics’ longitudinal cohort study

AU - Wabe, Nasir

AU - Meulenbroeks, Isabelle

AU - Firempong, Desiree Chantelle

AU - Urwin, Rachel

AU - Timothy, Andrea

AU - Raban, Magdalena Z.

AU - Mumford, Virginia

AU - Westbrook, Johanna

N1 - Copyright the Author(s) 2025. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

PY - 2025/6

Y1 - 2025/6

N2 - Aim: Our study aimed to identify trajectories of concurrent use of three psychotropic medication classes over time and identify predictors of trajectory group membership for residents with and without dementia. Findings: We conducted a retrospective longitudinal cohort study among residents in 30 RACFs in New South Wales, Australia and found that one in three residents with dementia and one in five residents without dementia concurrently use multiple psychotropics often for extended periods, which may put residents at risk. Message: Considering a concerning high rate of concurrent use of multiple psychotropic medicines in RACFs, it is imperative to assess its appropriateness and consider further research and strategies for improved health outcomes.

AB - Aim: Our study aimed to identify trajectories of concurrent use of three psychotropic medication classes over time and identify predictors of trajectory group membership for residents with and without dementia. Findings: We conducted a retrospective longitudinal cohort study among residents in 30 RACFs in New South Wales, Australia and found that one in three residents with dementia and one in five residents without dementia concurrently use multiple psychotropics often for extended periods, which may put residents at risk. Message: Considering a concerning high rate of concurrent use of multiple psychotropic medicines in RACFs, it is imperative to assess its appropriateness and consider further research and strategies for improved health outcomes.

KW - Aged care

KW - Nursing homes

KW - Medication use

KW - Group-based multi-trajectory modelling

KW - Psychotropics

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SN - 1878-7649

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Wabe N , Meulenbroeks I, Firempong DC, Urwin R, Timothy A, Raban MZ et al. Identifying long-term patterns and predictors of concurrent psychotropic medicine use in residential aged care using group-based multi-trajectory modelling: the ‘MEDTRAC-Psychotropics’ longitudinal cohort study. European Geriatric Medicine. 2025 Jun;16(3):781-792. Epub 2025 Feb 25. doi: 10.1007/s41999-025-01171-6

Identifying long-term patterns and predictors of concurrent psychotropic medicine use in residential aged care using group-based multi-trajectory modelling: the ‘MEDTRAC-Psychotropics’ longitudinal cohort study

Abstract

Bibliographical note

Keywords

Access to Document

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Fingerprint

Projects

A National Aged Care Medication Roundtable - Translating aged care data into action to improve quality of care through collaboration and co-design

Optimising eHealth systems to improve medication safety and patient outcomes

Cite this