Lucilia cuprina genome unlocks parasitic fly biology to underpin future interventions

Clare A. Anstead, Pasi K. Korhonen, Neil D. Young, Ross S. Hall, Aaron R. Jex, Shwetha C. Murali, Daniel S.T. Hughes, Siu F. Lee, Trent Perry, Andreas J. Stroehlein, Brendan R.E. Ansell, Bert Breugelmans, Andreas Hofmann, Jiaxin Qu, Shannon Dugan, Sandra L. Lee, Hsu Chao, Huyen Dinh, Yi Han, Harsha V. DoddapaneniKim C. Worley, Donna M. Muzny, Panagiotis Ioannidis, Robert M. Waterhouse, Evgeny M. Zdobnov, Peter J. James, Neil H. Bagnall, Andrew C. Kotze, Richard A. Gibbs, Stephen Richards, Philip Batterham, Robin B. Gasser*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

45 Citations (Scopus)
10 Downloads (Pure)

Abstract

Lucilia cuprina is a parasitic fly of major economic importance worldwide. Larvae of this fly invade their animal host, feed on tissues and excretions and progressively cause severe skin disease (myiasis). Here we report the sequence and annotation of the 458-megabase draft genome of Lucilia cuprina. Analyses of this genome and the 14,544 predicted protein-encoding genes provide unique insights into the fly's molecular biology, interactions with the host animal and insecticide resistance. These insights have broad implications for designing new methods for the prevention and control of myiasis.

Original languageEnglish
Article number7344
Pages (from-to)1-11
Number of pages11
JournalNature Communications
Volume6
DOIs
Publication statusPublished - 25 Jun 2015
Externally publishedYes

Bibliographical note

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