Image-based computational hemodynamics of distal aortic arch recoarctation following the Norwood procedure

J. L. Liu*, K. Itatani, R. Shiurba, T. Miyakoshi, Y. Qian, A. Murakami, K. Miyaji, M. Umezu

*Corresponding author for this work

    Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionpeer-review

    8 Citations (Scopus)

    Abstract

    Currently, few applications of computational hemodynamics predict outcomes after palliative surgery for congenital heart defects such as hypolastic left heart syndrome in infants. Here, we report on three-dimensional imaging methods for modeling recoarctation that commonly occurs in the distal aortic arch following the Norwood procedure. We used computer-aided design to simulate seven stages of increasing stenosis, analyze the resulting hemodynamics, and visualize the impairment of blood flow. A disproportionate drop in pressure occurred when stenosis reached 20% of the cross-sectional area of the descending aorta. The corresponding decrease in blood flow in the descending aorta was relatively small, however. Accordingly our findings suggest a reasonable approach to this phenomenon is watchful waiting rather than immediate surgical intervention. Such patient-specific predictions appear to be valuable for minimizing the risks of corrective surgery. These methods also may be applied to procedures for alleviating other congenital heart defects.

    Original languageEnglish
    Title of host publication2011 4th International Conference on Biomedical Engineering and Informatics (BMEI 2011)
    EditorsYongsheng Ding
    Place of PublicationNew York
    PublisherInstitute of Electrical and Electronics Engineers (IEEE)
    Pages318-323
    Number of pages6
    Volume1
    ISBN (Electronic)9781424493524, 9781424493500
    ISBN (Print)9781424493517
    DOIs
    Publication statusPublished - 2011
    Event2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011 - Shanghai, China
    Duration: 15 Oct 201117 Oct 2011

    Other

    Other2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011
    CountryChina
    CityShanghai
    Period15/10/1117/10/11

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