Image registration: An essential tool for nuclear medicine

Brian F. Hutton*, Michael Braun, Lennart Thurfjell, Dennys Y. Lau

*Corresponding author for this work

    Research output: Contribution to journalReview articlepeer-review

    114 Citations (Scopus)


    There is increasing interest in being able to automatically register medical images from either the same or different modalities. Registered images are proving useful in a range of applications, not only providing more correlative information to aid in diagnosis, but also assisting with the planning and monitoring of therapy, both surgery and radiotherapy. The practising nuclear medicine specialist is faced with a dilemma in choosing an appropriate method since the literature in the field is extensive, with conflicting evidence as to what methods are optimal. Although most barriers to implementing registration in routine practice have been removed, there remains a lack of commercial, validated software. The alternative is to install a dual-modality instrument. The objective of this review is to present a general overview of medical image registration with emphasis on the application and issues relevant to nuclear medicine.

    Original languageEnglish
    Pages (from-to)559-577
    Number of pages19
    JournalEuropean Journal of Nuclear Medicine
    Issue number4
    Publication statusPublished - 2002


    • Anatomical/functional comparison
    • Emission tomography
    • Image fusion
    • Image registration
    • Multimodality comparison


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